Nitric Oxide Releasing Coatings to Prevent Catheter Related Healthcare Associated Infections

该项目旨在探索使用一种称为金属有机框架（MOFs）的新型化合物从导管涂层内输送生物活性气体一氧化氮（NO）的可行性。其目的是预防导管相关的血流和尿路感染，这导致每年数百万的医疗保健相关感染。如果成功，该技术将提高患者的护理质量，降低感染率和死亡率，并减轻医疗保健提供者因这些感染而延长住院和术后护理的经济负担。

This project aims to explore the feasibility of using a new class of chemical compound called Metal Organic Frameworks (MOFs) to deliver the bio-active gas nitric oxide (NO) from within coatings on catheters. The purpose is to prevent catheter related blood stream and urinary tract infections, which contribute to the millions of incidences of Healthcare Associated Infection each year. If successful, the technology will improve patients' quality of care, reduce infection and mortality rates and reduce the financial burden on Health Care Providers associated with prolonged hospitalisation and after care as a result of these infections.