Developing new <1mm microneedle sensors to actively and painlessly monitor the key indicators of energy levels, metabolism and fatigue in biomarkers under the skin in real-time

人体是独一无二的，每个人都有不同的新陈代谢需求、能量消耗以及对运动和食物的不同反应。由于人们目前依赖于提供心率、体重和运动数据等通用数据的可穿戴设备，目前在实验室之外无法量化饮食、水分和锻炼对身体的影响。尽管可穿戴技术市场到2022年仍在快速增长215亿GB(2.33亿单位销售额)，该领域的创新已经放缓([福布斯：2018][0])，绝大多数设备仍然配备与10年前相同的传感器(GPS心率加速计)。我们是一家总部位于帝国理工学院伦敦帝国理工学院翻译和创新中心的传感器初创公司，开发创新的个性化健康和福祉传感器设备。我们打算与拉夫堡运动科学部和英国铁人三项运动员合作，开发世界上第一个分子性能跟踪器--实时监测人体皮肤下真皮间质液体中的生物标记物，提供关于能量、新陈代谢、疲劳、血糖水平和饮食的见解，以帮助优化训练、改善饮食、防止疲劳和降低疲劳相关伤害的风险。实时监测人体生物标记物的能力具有显著的更广泛的潜力，作为个人健康监测器-帮助人们了解何时进食、补充水分、REST等(个人和军事市场)，并作为医疗设备-提供对健康状况的生物标志物指标的实时监测(例如糖尿病、败血症等)[0]：https://www.forbes.com/sites/paullamkin/2018/10/23/smart-wearables-market-to-double-by-2022-27-billion-industry-forecast/#3231bbac2656

The human body is unique, with each person having varying metabolic needs, energy expenditure and a diverse response to exercise and food. Quantifying how diet, hydration and exercise impact our bodies in such singular ways is currently impossible outside of the lab, with people currently reliant on wearables that provide generic data such as heart-rate, body weight and movement data.Whilst the wearable technology market is still rapidly growing £21.5bn by 2022 (233m\_unit\_sales), innovation in the sector has slowed ([Forbes:2018][0]) and the vast majority of devices still feature the same sensors (GPS\_heart rate\_accelerometer)as 10 years ago.We are a sensor start-up based at the Imperial College London Translation and Innovation Hub that develops innovative personalised health and wellbeing sensor devices. Working in partnership with Sports Science department of Loughborough and British Triathlon athletes, we intend to develop the world's first molecular performance tracker - monitoring biomarkers in the bodies' dermal interstitial fluid just below the skin in real-time, to provide insights on energy, metabolism, fatigue, blood-sugar level and diet to help optimise training, improve diet, prevent exhaustion and reduce the risk of fatigue-related injury.The ability to unobtrusively monitor the bodies' biomarkers in real-time has significant wider potential as both a personal health monitor- helping people understand when to eat, hydrate, rest etc. (personal & military markets) and as a medical device- providing real-time monitoring of biomarkers indicators of health conditions (e.g. diabetes, sepsis etc.)[0]: https://www.forbes.com/sites/paullamkin/2018/10/23/smart-wearables-market-to-double-by-2022-27-billion-industry-forecast/#3231bbac2656