Shining a Light on Brain Temperature with Near-Infrared Nanosensors

该项目旨在开发一种基于近红外荧光的非接触式测温方法，以实时绘制大脑或神经温度。这项研究希望利用光学、纳米技术和材料科学的工具在神经科学领域产生新的知识。该项目产生的技术有望量化不同情况下神经系统的瞬时局部加热，并研究这如何影响神经功能。预计这将带来显著的益处，有助于制定监管框架，确保安全实施神经系统和神经退行性疾病的新疗法。

This project aims to develop a contactless thermometry approach based on near-infrared fluorescence to map brain or nerve temperature in real-time. This research expects to generate new knowledge in the field of neuroscience using tools from optics, nanotechnology and materials science. The technique generated as a result of this project is expected to enable the quantification of the transient local heating of the nervous system in different situations and the study of how this affects neural function. This is expected to provide significant benefits, enabling the development of regulatory frameworks that ensure the safe implementation of new therapies for neurological and neurodegenerative disorders.