STRUCTURE/FUNCTION ANALYSIS OF YEAST MITOCHONDRIAL HSP70

对分子伴侣在细胞凋亡中的作用的进一步认识 介导蛋白质折叠具有基本的生物学意义，但可能 也有助于更好地了解一些疾病，如癌症。 吉姆·罗斯曼的部门在分子伴侣领域处于领先地位 和催化蛋白质折叠（见应用程序），因此是理想的 在这个领域进行培训。 我认为，做好后... 博士工作在这个杰出的实验室是一个独特的机会，学习 结构-功能研究的最新技术和方法 分子伴侣，细胞生物学和蛋白质化学，这将是高度 对我的研究事业很有价值

A better understanding of the function of molecular chaperones in mediating protein folding is of fundamental biological interest, but may also contribute to better understanding of some diseases such as cancer. Jim Rothman's department is leading in the field of molecular chaperones and catalyzed protein folding (see application), and is thus the ideal place for training in this area. It is my belief that doing post- doctoral work in this outstanding laboratory is a unique chance to learn state of the art techniques and approaches in structure-function studies of chaperones, cell biology, and protein chemistry, which will be highly valuable for my research career.