MASTER AGREEMENT FOR CHEMICAL SYNTHESIS
MASTER AGREEMENT FOR CHEMICAL SYNTHESIS
批准号:
3608080
负责人:
DRURY S CAINE
金额:
$0.42万
依托单位国家:
美国
项目类别:
财政年份:
1992
资助国家:
美国
项目状态:
未结题
起止时间:
1992-12-16 至
关键词:
analytical chemistry antiAIDS agent antineoplastics chemical synthesis drug design /synthesis /production drug metabolism drug screening /evaluation heterocyclic compounds infrared spectrometry neoplasm /cancer pharmacology nuclear magnetic resonance spectroscopy nucleosides peptides ultraviolet spectrometry
中文摘要
承包商应按照政府的要求,向船长提供
在约定顺序的基础上,指定具体化合物。分配给
合成材料,以及标准的说明
纯度和数量将由项目官员提供。具体来说,
承包商应执行以下任务:1)重新合成
指定化合物,一半(0.5)至两(2)克量和/或
合成一半(0.5)到两(2)克量的独特化合物。
将所有合成的化合物提交给NCI。2)建立……身份
每种化合物均通过红外光谱、紫外光谱、核磁共振谱、元素分析等手段合成。3)
对所有材料进行完全的纯度和均一性检测。
测定溶解度和稳定性等物理化学性质
视需要而定。4)提交所有合成化合物的数据表,给出
相关的化学和物理性质,其格式为
项目官员。5)所有目标化合物必须在
主协议订单发布后的建议时间段。在……里面
在特殊情况下,可经双方同意延长
承包人和承包人。6)应使用的化学品和药物
根据本主协议准备或处理的应被视为
在性质上是私有的。在任何情况下,化学品或药物或
任何与这些化学品或药物有关的信息将被公布或
未经项目官员事先书面批准而泄露。
英文摘要
The contractor shall furnish as required by the Government, on a master
agreement order basis, the specific compounds assigned. Assignment of
materials for synthesis, as well as the specification of standards of
purity and quantity will be provided by the project officer. Specifically,
the contractor shall perform the following tasks: 1) Resynthesize
specified compounds in half (0.5) to two (2) gram quantities and/or
synthesize unique compounds in half (0.5) to two (2) gram quantities.
Submit all compounds synthesized to NCI. 2) Establish the identity of
each compound synthesized through IR, UV, NMR, and elemental analysis. 3)
Assay completely all materials as to their purity and homogeneity.
Determine physical and chemical properties such as solubility and stability
as required. 4) Submit data sheets for all compounds synthesized, giving
pertinent chemical and physical properties in a format acceptable to the
project officer. 5) All target compounds must be delivered within the
proposed time period after issuance of the master agreement order. In
exceptional cases, it may be extended by the mutual agreement of the
Contracting Officer and the Contractor. 6) The chemicals and drugs to be
prepared or handled under this Master Agreement are to be regarded as
proprietary in nature. Under no circumstances are chemicals or drugs or
any information associated with these chemicals or drugs to be released or
divulged without prior written approval of the Project Officer.
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MASTER AGREEMENT ORDER FOR CHEMICAL SYNTHESIS
-
批准号:3608077
-
项目类别:
-
资助金额:$1.86万
-
财政年份:1992
-
负责人:DRURY S CAINE
-
依托单位:
PURCHASE OF A HIGH RESOLUTION MASS SPECTROMETER
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批准号:3520326
-
项目类别:
-
资助金额:$40.0万
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财政年份:1989
-
负责人:DRURY S CAINE
-
依托单位:
SYNTHESIS OF ANTICANCER HELIANGOLIDES
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批准号:3182419
-
项目类别:
-
资助金额:$4.78万
-
财政年份:1987
-
负责人:DRURY S CAINE
-
依托单位:
SYNTHESIS OF ANTICANCER HELIANGOLIDES
-
批准号:3182416
-
项目类别:
-
资助金额:$5.1万
-
财政年份:1987
-
负责人:DRURY S CAINE
-
依托单位:
SYNTHESIS OF ANTICANCER HELIANGOLIDES
-
批准号:3182418
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项目类别:
-
资助金额:$4.93万
-
财政年份:1987
-
负责人:DRURY S CAINE
-
依托单位:
海外基金