SIXTH INTERNATIONAL WORKSHOP ON PLASMINOGEN ACTIVATION

这是一项支持1997年VITH国际会议的建议， 纤溶酶原分子和细胞生物学研讨会 Activation. 纤溶酶原激活（PA）仍然是一个核心的 心、肺和血液疾病治疗的重点，以及 纤溶酶原激活剂药物已经成为 治疗心肌梗塞、中风和其他 血栓栓塞性疾病 因此，PA的研究处于界面 科学研究、临床医学和生物技术。 基础实验室的贡献尤其突出， 这对该领域新疗法的发展至关重要。 的 PA研讨会为研究人员提供了一个独特的机会 来自世界各地的人在一个小的 所有参与者都居住在其中的非正式环境。 这一系列PA研讨会的一个独特之处在于， 过去和将来的会议主要是以抽象为导向的。 因此，与大多数其他会议相比， 目前在该领域的工作将得到强调， 将避免审查已经公布的数据。 爆炸 对这一领域的兴趣导致了第一个PA的组织 1987年的讲习班以及第一次会议和随后的两年期会议 会议得到了与会者的广泛参与和重视 取得了巨大的成功 第六届PA研讨会将于 1997年11月1日至6日在加州科罗纳多。 部分供资 在这份申请中要求参加这次会议。 鉴于 科学和临床发展的持续快速发展， PA领域，因为它涉及心脏、肺、脑 肾脏等，这次会议应该再次非常适当 而且及时 本次会议将有一个独特的重点，因为它将 强调PA在生理和病理生理中的作用 除血栓溶解外。 其中包括神经 功能，动脉粥样硬化，血管生成，血管生成，肥胖和 癌症，并将汇集对生物学感兴趣的科学家， PA的生物化学和遗传学。 我们预计， 本次会议将进行的互动和讨论将 帮助确定重要的新方向，问题， 未来研究的技术。

This is a proposal to support the 1997 VITH International Workshop on Molecular and Cellular Biology of Plasminogen Activation. Plasminogen activation (PA) continues to be a central focus for therapeutic in heart, lung, and blood diseases, and plasminogen activator pharmaceuticals have become a mainstay for the treatment of myocardial infarction, stroke, and other thromboembolic disorders. The study of PA thus is at the interface of scientific research, clinical medicine, and biotechnology. Contributions from the basic laboratory have been particularly important for the development of new therapies in this field. The PA Workshop has provided an unique opportunity for investigators from around the world to interact and exchange ideas in a small informal environment in which all participants are in residence. One unique aspect of this series of PA Workshops is that they have been and will continue to be primarily abstract-driven meetings. Therefore, and in contrast to most other meetings, the most exciting and current work in the field will be emphasized, and lengthy reviews of already published data will be avoided. The explosive interest in this field led to the organization of the first PA Workshop in 1987 and the initial meeting and subsequent biannual meetings have been well attended and regarded by the participants as resounding successes. The VIth PA Workshop will be held in Coronado, California from November 1-6, 1997. Partial funding for this meeting is requested in this application. Given the continued rapid pace of scientific and clinical developments in the field of PA as it pertains to diseases of the heart, lung, brain, kidneys, etc., this meeting should again be extremely appropriate and timely. This meeting will have an unique focus in that it will emphasize the role of PA in physiological and pathophysiological processes in addition to thrombolysis. These include neural functions, atherogenesis, angiogenesis, vasculogenesis, obesity and cancer, and will bring together scientists interested in the biology, biochemistry and genetics of PA. We anticipate that the extensive interactions and discussions which will occur at this meeting will help to identify important new directions, problems, and technologies for future research.