MAMMALIAN BRAIN MAST CELLS AND REPRODUCTION

这里描述的研究旨在调查参与 脑肥大细胞在男性叙利亚人生殖功能中的作用 仓鼠 仓鼠是一个有吸引力的模型来研究的作用， 促性腺激素释放激素免疫阳性（GnRH+）肥大细胞， 大脑中这些细胞的数量受到生殖系统的影响， 动物的状态（即，在光刺激中看到更多的细胞， 生殖活跃的男性）。 细胞数量和细胞数量之间 在鸽子身上也发现了繁殖能力， 脊椎动物的共同特征。 本研究的目的是（1）确认 GnRH+非神经元细胞作为肥大细胞的表型， 电子显微镜检查，（2）确定GnRH+肥大细胞是否诱导 大脑是类固醇不依赖的，（3）确定相关的社会性别 GnRH+肥大细胞迁移到大脑中的条件。

the research described here is intended to investigate the involvement of brain mast cells in the reproductive functions of male Syrian hamsters. The hamster is an attractive model to investigate the role of gonadotropin releasing hormone immunopositive (GnRH+) mast cells because the number of these cells in the brain is affected by the reproductive status of the animal (i.e., more cells are seen in photostimulated, reproductively active males). A similar correlation between cell number and reproductive competence has also been seen in doves and may be a common feature in vertebrates. The aims of this study are to (1) Confirm the phenotype of the GnRH+ non-neuronal cells as mast cells using electron microscopy, (2) Determine if GnRH+ mast cell induction in the brain is steroid-independent, and (3) Determine the relevant socio-sexual conditions under which GnRH+ mast cells migrate into the brain.