Inova Design Solutions Ltd: Non-Invasive Continuous Core Temperature Monitor ("NCCTM")

这个概念验证（“PoC”）项目是技术战略委员会最近授予的可行性研究（项目131336）的下一阶段发展。NCCTM的原理验证原型成功地展示了该技术的基本功能，初步测试显示了预期的结果。这项技术旨在预防中暑，尤其是中暑衰竭和死亡。由于在恶劣环境中体力消耗或无法控制环境，个人可能会患中暑。在活动和不活动期间，对非侵入性监测的需求仍未得到满足。英国市场估计为9500万英镑，欧洲市场为4.74亿英镑（1-4）。提出的创新是一种便携式，医学上准确的，非侵入性的设备，可以连续和自动实时监测个人的核心体温（“c.b.t.”），从而避免热疾病，并使生理功能在安全和最佳水平上运行。目前还没有测量核心体温的方法提供这种综合功能，由此产生的产品将显著改善当前的患者护理，并使生理学监测的许多新的门诊应用能够大大增加从全球市场中受益于温度监测的个人数量，从医疗保健到国防。这个PoC项目的主要目标是(A)设计和建造一个工程原型，(B)对原型进行验证测试，以及(C)生成新的IP。随着验证的成功，该技术将准备进行预生产开发和开发许可和直接销售。(1) Frost & Sullivan，健身生命体征监测：比赛才刚刚开始！(2) Frost & Sullivan，欧洲ALT市场，2010年(3)欧洲防务局，EDA参与成员国防务数据，2011年(4)Frost & Sullivan，欧洲温度监测设备市场，2006年

This proof of concept (“PoC”) project is the next phase of development of a recently awardedfeasibility study from the Technology Strategy Board (project 131336). The proof of principleprototype of the NCCTM successfully demonstrates basic functionality of the technology andinitial tests show desired results.The technology is designed to prevent heat illness, particularly heat exhaustion and death.Individuals may suffer heat illness as a result of physical exertion in harsh environments orthe inability to control their environment. There is a major unmet need for non-invasivemonitoring during activity and inactivity. The available UK market is an estimated £95m, andEuropean market £474m (1-4).The innovation presented is a portable, medically accurate, non-invasive device tocontinuously and automatically monitor the core body temperature (“c.b.t.”) of individuals inreal-time so that heat illness can be avoided and physiological functions operate at a safe andoptimal level.There are no existing methods of measuring core body temperature that provide this combinedfunctionality and the resultant products will significantly improve current patient care andenable many new ambulatory applications of physiology monitoring to vastly increase thenumber of individuals who can benefit from temperature monitoring, in global markets fromhealthcare to defence.The key objectives of this PoC project are to (A) design and build an engineering prototype,(B) carry out validation testing of the prototype, and (C) generate new IP. With successfulvalidation the technology would be ready for pre-production development and exploitation vialicensing and direct sales.(1) Frost & Sullivan, Fitness Vital Signs Monitoring: The Race Has Just Begun!, 2008(2) Frost and Sullivan, European markets for ALT, 2010(3) European Defence Agency, Defence Data of EDA participating Member States, 2011(4) Frost & Sullivan, European Temperature Monitoring Devices Market, 2006