LOW COST FETAL STRESS DIGITAL MAGNETOCARDROGRAPH SYSTEM

我们建议开发允许成本的仪器能够记录 胎儿心磁图（Fetal-MCG）。 这种完全非侵入性的 仪器旨在有助于评估胎儿应力 以及胎儿心律失常的诊断。 胎儿MCG系统 提供难以或不可能获得的独特信息 任何其他工具。 HYPRES，Inc.，的世界领导者 超导电子公司，正在与生物磁公司合作这个项目。 技术公司，生物磁力计的先驱和领先供应商 系统. 教授约翰Wikswo的第一次，数字SQUID的 系统的关键传感器组件。 使用这种新的数字 SQUID技术将大大降低系统的成本， 消除了对非常昂贵的屏蔽ROM的需要 电子设备 在第一阶段项目中，我们开发并 演示了数字SQUID电路的所有组件，设计 完整的系统，并计算了预期的系统性能 特色 在第二阶段，我们将生产和展示至少一个 适合启动详细临床研究的完整原型。 拟议的商业应用： 开发的仪器有可能成为一个重要的工具， 来诊断胎儿压力 数字SQUID在此 仪器将导致胎儿MCG系统成本的显著节省 由于消除了对屏蔽室的需要， 简化电子设备。 他的成功示范 这里的数字SQUID技术也将为 商业化到其他生物磁力计应用中，包括 磁源成像（MSI）定位手术或 癫痫治疗，并定位心脏致瘤组织或 确定患者有心脏性猝死的风险。

We propose the development of allow cost instrument capable of recording the fetal magnetocardiogram (fetal-MCG). This totally non-invasive instrument is intended to contribute to the assessment of fetal stress and the diagnosis of fetal cardiac arrhythmias. The fetal-MCG system provides unique information that is difficult or impossible to obtain with any other instrument. HYPRES, Inc., a world leader in superconducting electronics, is teaming for this project with Biomagnetic Technologies, Inc., the pioneer and leading supplier of biomagnetometer systems. Professor John Wikswo of the first time, digital SQUIDs for the critical sensor component of the system. The use of this new digital SQUID technology will dramatically reduce the cost of the system by eliminating the need for very expensive shielded rom and by simplifying the electronics. In the Phase I project, we have developed and demonstrated all of the components of the digital SQUID circuit, designed the complete system, and calculated the expected system performance characteristics. In PhaseII we will produce and demonstrate at least one complete prototype suitable to initiate detailed clinical studies. PROPOSED COMMERCIAL APPLICATIONS: The instrument developed has the potential of becoming as essential tool for diagnosing fetal stress. The use of digital SQUIDs in this instrument will lead to significant saving in the fetal-MCG system cost due to the elimination of the need for a shielded room and the simplication of the electronics. The successful demonstration of he digital SQUID technology here would also open the door for commercialization into other biomagnetometer applications including Magnetic Source Imaging (MSI) to localize brain function for surgery or epilepsy treatment, and to localize cardiac arrhythmogenic tissue or to determine patients at risk for sudden cardiac death.