FASEB CONFERENCE--FOLATE, B12 AND ONE CARBON METABOLISM

请求提供资金，以部分支持第七届FASEB夏季 叶酸、维生素B12和一碳研究会议 代谢，将在美国人联合会的主持下举行 实验生物学学会（FASEB），1998年8月1日至8月6日 在科罗拉多的斯诺马斯村本次会议提供了一个独特的 为临床科学家、基础科学家和那些 参与科学政策的一个广泛的学科群体， 对叶酸、维生素B12和一碳代谢感兴趣， 正式和非正式的互动。 过去五次会议 已全部订阅，参加本次会议将是 仅限180人。 要求资金允许毕业生 学生，居民和博士后研究员和建立国家 和国际科学家参加会议。 详细的计划 其中包括知名科学家和初级 科学家们刚刚进入这个领域。 此外，主题扫描整个 从目前的临床问题到最严重的领域， 复杂的生物化学和生物物理研究。 班 单碳代谢的时间表：酶学和调节; 同型半胱氨酸代谢和调节;蛋氨酸和叶酸辅因子 甲基转移、DNA、修复和 癌发生;叶酸和维生素的细胞和上皮转运 B 12;叶酸依赖性酶反应;叶酸、维生素B12和 中枢神经系统：发育、衰老和认知;叶酸和B12 合成，化疗的新靶点;遗传异质性， 叶酸和维生素B12的需求。 除了正式 介绍，该计划将补充海报会议， 工作坊.这些会议为非正式讨论提供了许多机会， 允许研究生，居民和博士后研究员，以及 建立科学家，有机会提出和讨论他们的 工作 与过去一样，最有趣的新研究在 会议将以下列形式向更广泛的受众传播： 一个或多个“国家的最先进的”评论在FASEB杂志。

Funds are requested for partial support of the Seventh FASEB Summer Research Conference on Folic Acid, Vitamin B12 and One Carbon Metabolism, to be held under the auspices of the Federation of American Societies for Experimental Biology (FASEB) from August 1- August 6, 1998 at Snowmass Village, Colorado. This conference offers a unique opportunity for clinician scientists, basic scientists, and those involved in science policy from a broad group of disciplines with an interest in folic acid, vitamin B12 and one carbon metabolism, to interact both formally and informally. The last five conference have been fully subscribed and participation at this conference will be limited to 180 individuals. Funds are requested to allow graduate students, residents and postdoctoral fellows and established national and international scientists to attend the meeting. A detailed program is presented which includes well established scientists and junior scientists just entering the field. In addition, topics scan the entire spectrum from current clinical problems to areas of the most sophisticated biochemical and biophysical research. Sessions have been scheduled on one carbon metabolism: enzymology and regulation; homocysteine metabolism and regulation; methionine and folate cofactor as synthesis/regulation; methyl transfer, DNA, repair and carcinogenesis; cellular and epithelial transport of folate and vitamin B 12; folate dependent enzyme reactions; folate, vitamin B12, and the central nervous system: development aging, and cognition; folate and B12 synthesis, new targets for chemotherapy; and genetic heterogeneity and folate and vitamin B12 requirements. In addition to the formal presentations, the program will be complemented with poster sessions and workshops. These offer many opportunities for informal discussion and allow graduate students, residents and postdoctoral fellows, as well as established scientists, an opportunity to present and discuss their work. As in the past, the most interesting new research presented at the conference will be disseminated to a much wider audience in the form of one or more "state-of-the-art" reviews in the FASEB Journal.