GR CONFERENCE--DNA ALTERATIONS IN TRANSFORMAL CELLS

描述(申请人描述)：本申请是部分申请 将资助一项名为“转化细胞中的DNA改变”的会议 在戈登研究会议(GRC)的赞助下于 科尔比-索耶学院，1998年8月9日至14日。这将是第二次 在一个特别激动人心的时刻召开关于这一主题的两年一次的全球资源中心会议 对于这一广阔领域中的许多子学科。在这次会议上， 与会者(最多130人)致力于蜂窝技术的各个方面 变形将能够相互作用。这次会议的一个主要目标是 促进那些研究遗传和表观遗传因素的人之间的对话 致癌。会议将有九个演讲者会议和每日 海报会议。从提交的摘要中，海报演示者以及 大约六位演讲者将被挑选出来。因此，本次大会将 为年轻的调查人员以及国际上的调查人员提供一个良好的论坛 著名资深科学家，介绍他们的研究成果。在……里面 此外，在这一系列的第一次会议上，将会有一个沉重的 强调正式讨论，留出15-20分钟用于讨论 每一次演讲和讨论后，领导都会提前准备好刺激 与会者提出的问题和意见。这次会议将提供一个 研究遗传性癌症综合征和DNA的研究人员汇聚一堂 甲基化，印迹，DNA修复，端粒酶，核型不稳定性， 乳腺癌、细胞凋亡以及内源性和荷尔蒙对 癌症的发展和肿瘤的进展。最近的发现揭示了 将这些领域中的几个领域链接在一起的机制 调查人员可能会产生协同作用的进展。此外，范围很广， 这次会议将涵盖的调查将涵盖基础研究 转化性和临床研究。

DESCRIPTION (Applicant's Description): This application is for partial funding of a conference called "DNA Alterations in Transformed Cells" to be held under the auspices of the Gordon Research Conferences (GRC) at Colby-Sawyer College from August 9 to 14, 1998. This will be the second biennial GRC conference on this topic during a particularly exciting time for many of the subdisciplines in this broad field. At this conference, the attendees (130 maximum) working on various aspects of cellular transformation will be able to interact. A major goal of this conference is to promote dialogue between those studying genetic and epigenetic factors in carcinogenesis. The meeting will feature nine speaker sessions and daily poster sessions. From submitted abstracts, the poster presenters as well as about six of the speakers will be chosen. Therefore, this conference will provide a good forum for younger investigators, as well as internationally renowned senior scientists, to present their research findings. In addition, as at the first conference in this series, there will be a heavy emphasis on formal discussion, with 15-20 minutes set aside for discussion after each talk and discussion leaders prepared in advance to stimulate questions and comments from participants. This conference will provide a meeting ground for investigators working on inherited cancer syndromes, DNA methylation, imprinting, DNA repair, telomerase, karyotypic instability, breast cancer, apoptosis, and endogenous and hormonal contributions to cancer development and tumor progression. Recent discoveries have uncovered mechanisms linking several of these fields so that cross-talk among investigators may yield synergistic advances. Furthermore, the wide range of investigations to be covered at this conference will span basic studies to translational and clinical studies.