FASEB CONFERENCE--MECHANISMS OF RNA MATURATION AND DECAY

这次为期五天的FASE B夏季研究会议的目标是 将处于研究前沿的科学家聚集在一起 一组相互关联的转录后调控过程：mRNA 3‘聚合体的降解、胞质加成、胞质去除及功能 (A)尾巴，以及rRNA和tRNA的加工和成熟。每一个 这些领域最近取得了令人兴奋的进展，极大地 影响了人们对这些关键生物过程的思考。尽管他们 调控在所有生物体中的重要性及其与人类的相关性 疾病，这些话题通常只受到肤浅的关注 其他会议。这次会议的一个主要特点是将 真核生物和原核生物系统。不包括任何类别的 生物体会强加不必要的区别，从而限制 思想的交融。转录后过程不是 会议讨论的内容将包括信使核糖核酸剪接、核 多聚腺苷酸化、信使核糖核酸定位和无关的翻译方面 到聚(A)或信使核糖核酸的降解；所有这些话题都受到相当大的关注 在其他会议上注意。 此前的五次此类会议都非常成功。 根据与该领域其他人的对话，没有与 类似的重点似乎也安排在1998年。召开一次会议 1998年，科学家们聚集在一起，研究这一机制，并 对这些密切相关的生化过程的调节 真核和原核细胞，我们希望提供一个论坛 对最新发现和理论的热烈讨论，将刺激 创新理念，推动科学协作，影响方向 该领域未来的研究成果。 为方便与会者之间的沟通，会议将于 限制在125人左右，预计每个人都将 参加整个会议。被邀请的演讲者将包括许多 这些领域中最多产和最具创新精神的研究人员。 年轻科学家(初级PI、博士后研究员和高级 研究生)也将被鼓励参加会议，以及 我们将为他们提供机会，让他们展示自己的 在会议的全体会议上进行研究。所有演讲者都将 被敦促专注于他们最新的未公布数据和新出现的假设 还有模特。

The goal of this five-day FASEB Summer Research Conference will be to bring together scientists at the forefront of research on an interrelated set of post-transcriptional regulatory processes: mRNA degradation, the cytoplasmic addition, removal, and function of 3' poly (A) tails, and the processing and maturation of rRNA and tRNA. Each of these fields has recently enjoyed exciting advances that have greatly influenced thinking about these key biological processes. Despite their regulatory importance in all organisms and their relevance to human disease, these topics typically receive only superficial attention at other meetings. A key feature of the conference will be the inclusion of both eukaryotic and prokaryotic systems. Excluding either class of organisms would impose an unnecessary distinction that would limit cross-fertilization of ideas. Post-transcriptional processes not to be covered at the conference will include mRNA splicing, nuclear polyadenylation, mRNA localization, and aspects of translation unrelated to poly(A) or mRNA degradation; all of these topics receive considerable attention at other meetings. Five previous conferences of this sort have been highly successful. Based on conversations with others in the field, no conferences with a similar focus appear to be scheduled for 1998. By convening a conference in 1998 that brings together scientists investigating the mechanism and regulation of these closely interrelated biochemical processes in eukaryotic and prokaryotic cells, we hope to provide a forum for a lively discussion of recent discoveries and theories that will stimulate new ideas, promote scientific collaboration, and influence the direction of future research in the field. To facilitate communication among the conferees, the meeting will be limited to about 125 participants, each of whom will be expected to attend the entire conference. The invited speakers will include many of the most productive and innovative researchers in these fields. Younger scientists (junior PIs, postdoctoral fellows, and senior graduate students) will also be encouraged to attend the meeting, and opportunities will be provided for them to be selected to present their research in the conference's plenary sessions. All speakers will be urged to focus on their latest unpublished data and emerging hypotheses and models.