UTILITY AND OUTCOMES FROM MAMMOGRAPHY IN NORTH CAROLINA

描述：(申请人的描述)这项工作的具体目的 研究内容有：1)比较乳房X光检查的临床实践 24名40岁以上女性的管理和筛查结果 特别参考黑人和黑人的差异的县人口 白人，城市和农村，50和50，以及女性子集 接受由BCCCP资助的乳房X光检查与普通 1995-2000年接受筛查的妇女人口；和2)描述 乳腺良性病变的分布及X线特征 根据种族、年龄和其他特征提出进一步的假设 研究。 在确定的基础上，提出了另外两个项目 Interval和Screen在这一人群中发现了癌症。具体的 这些项目的目的是：1)评估 间歇性癌症的乳房X光检查与筛查发现的癌症的比较；以及 2)比较Interval和Screen的组织化学特征 发现了癌症。 在24个县建立基于人群的乳房X光检查登记 位于北卡罗来纳州东部。人口中有很高比例的 黑人和农村妇女，给了我们做乳腺癌的机会 利用79例乳房X光摄影资料进行监测研究 在这一领域的实践。此数据链接到基于 病理数据库和北卡罗来纳州中央癌症登记中心(NC CCR)。将进行分析，以分析 卡罗莱纳州乳腺摄影登记处1995年1月至 2000年12月。妇女将从她们的筛查开始被清点 乳房X光检查，结果将通过两种机制确定： 1)来自登记关联数据的放射学随访；以及2)随访 针对转诊医生的努力。卡方分析将会是 进行比例数据检验；t检验将用于 将进行均值比较和Logistic回归分析 在适当的时候退出。

DESCRIPTION: (Applicant's Description) The specific aims of this research are: 1) To compare mammography screening practice, clinical management, and screening outcomes for the women over age 40 in the 24 county population with special reference to differences in Black versus White, urban versus rural, <50 versus >50, and the subset of women receiving mammography funded through the BCCCP versus the general population of screened women for the years 1995-2000; and 2) To describe the distribution and mammographic characteristics of benign pathology by race, age, and other characteristics to raise hypotheses for further research. Two additional projects are proposed based on the identification of interval and screen detected cancers in this population. The specific aims of these projects are: 1) to assess the image quality of the mammograms of interval cancers compared to screen detected cancers; and 2) to compare the histochemical characteristics of interval versus screen detected cancers. The creation of a population based mammography registry in 24 counties in eastern North Carolina. a population that has a high proportion of Black and rural women, gives us the opportunity to do breast cancer surveillance research using the data collected from 79 mammographic practices in this area. This data is linked to a population based pathology database, and the North Carolina Central Cancer Registry (NC CCR). Analyses will be conducted on the population accrued by the Carolina Mammography Registry for the time period January 1995 through December 2000. Women will be enumerated beginning with their screening mammogram, and their outcomes will be determined through two mechanisms: 1) radiologic follow up from registry linked data; and 2) follow up efforts aimed at the referring physicians. Chi square analyses will be carried out testing proportional data; t tests will be used for comparisons of means; and logistic regression analyses will be carried out when appropriate.