TEMPORAL AND BEHAVIORAL CONSTRAINTS ON PLASTICITY

皮质区域3b包含手指表面的表示 在未经训练的猫头鹰猴子中是相邻的和不重叠的。近期 梅泽尼奇实验室的研究表明，同时或 在行为任务中交替刺激手指会导致 这些数字的神经表示，以合并或分离， 分别进行了分析。在提议的实验中，我们问在什么时间下 行为条件将刺激的神经表征 合并？ 猫头鹰猴子已经接受了将刺激呈现给邻近区域的任务的训练 远端指垫具有几乎同时的刺激计时。苏醒 行为记录将允许我们记录大脑皮质的变化 伴随着动物感知能力的变化。《觉醒》 录音将回答有关时间和行为的问题 单个皮质神经元重新组织其空间的条件 和时间响应特性。

Cortical area 3b contains representations of the surfaces of the digits that are adjacent and non-overlapping in untrained owl monkeys. Recent work in the Merzenich laboratory has shown that simultaneous or alternating stimulation of the digits in a behavioral task causes the neural representations of these digits to merge or to segregate, respectively. In the proposed experiments we ask under what temporal and behavioral conditions will the neural representations of stimuli merge? Owl monkeys have been trained at tasks that present stimuli to adjacent distal fingerpads with near simultaneous stimulus timing. Awake behaving recordings will allow us to document the cortical changes that accompany changes in the animal's perceptual capabilities. The awake recordings will answer questions about the temporal and behavioral conditions under which single cortical neurons re-organize their spatial and temporal response properties.