GENES, ENVIRONMENT, AND MATERNAL ADJUSTMENT

描述（改编自申请人摘要）：拟定的研究目的 研究家庭过程和母亲适应之间的联系， 遗传信息设计，行为遗传学分析和技术， 评估家庭过程。 这项研究将是第一个使用这个 测试任何联系家庭过程的综合模型的综合方法 精神健康 关于家庭系统的最新研究结果将 以及行为遗传学的重大进展， 将母亲的心理健康与（1）稳定的心理属性联系起来 如性格和气质，（2）与她的关系 目前的家庭，包括她的婚姻和与孩子的关系 （3）她丈夫的特征及其与她的关系 孩子 该研究将使用足够大的基于人口的样本， 提供足够的动力来进行严格的测试：瑞典双胞胎 注册表 这项研究将采用最先进的家庭过程测量方法 包括母亲与孩子、父亲与孩子以及婚姻的视频记录， 家庭环境中的互动。 这项研究将由一个小组进行， 三个地点：乔治华盛顿大学，卡罗林斯卡学院， 斯德哥尔摩和隆德大学。 分析模型将侧重于 （1）特定的个体，遗传特征， 父母与子女及婚姻关系的变化;（2）如何 关系可能介导遗传对精神病理学的影响;（3） 在每个姐妹的环境中的社会经验是一个独特的 （非共有的）对她发展的一系列影响。

DESCRIPTION (Adapted from applicant's abstract): The proposed research aims to study the links between family process and maternal adjustment using a genetically-informed design, behavioral genetics analyses and techniques for assessing family process. This study will be the first to use this integrative approach to test any comprehensive model linking family process to mental health. Recent findings from research on family systems will be used, as well as major advances in behavioral genetics, to develop a model linking mother's mental health to (1) her stable psychological attributes such as personality and temperament, (2) to her relationship with her current family including her marriage and relationships with her children and (3) to characteristics of her husband and his relationship with her children. The study will use a population-based sample large enough to provide power adequate for a rigorous test of this model: The Swedish Twin Registry. The study will employ state-of-the-art measures of family process including video recording of mother-child, father-child, and marital interaction in the home setting. The study will be conducted by a team at three sites: George Washington University, Karolinska Institute in Stockholm and Lund University. Analytic models will focus on the delineation (1) of specific individual, heritable traits which elicit variations in parent-child and marital relationships; (2) of how relationships may mediate genetic effects on psychopathology; and (3) of social experiences in each sister's environment which are a unique (nonshared) set of influences on her development.