EATING DISORDERS IN YOUNG WOMEN--PREVALENCE AND RISK

描述(改编自申请者摘要)：饮食失调 反复暴饮暴食(暴饮暴食障碍)构成了一个重要的 对年轻女性的健康和心理调整的风险。当前 暴饮暴食障碍的知识受到a)虚拟排斥的限制 研究样本中的少数族裔妇女；b)缺乏对妇女的研究 患有谱系暴食症；以及c)过度依赖风险 风险暴露回溯性评估的因素研究。作为目标一号， 这项拟议的研究将评估2379名青年黑人和白人的队列 女性描述暴饮暴食障碍的谱系。vbl.使用 最先进的案件发现采访方法，我们将确定 神经性暴食症(BN)、暴饮暴食障碍(BED)的患病率及其 频谱变体(定义为满足所需标准中除一项以外的所有标准 用于完整的证候诊断)；我们还将识别当前轴的存在 我有精神障碍。目的：确定BN、BED和BED的临床意义 在这个基于社区的样本中，我们将比较它们的光谱变体 暴饮暴食障碍的女性和健康对照的衡量标准 肥胖与心理调适。种族和种族的联系 进食障碍病例和对照的伴随变量将是 检查过了。这项研究的目的二是开发一种基于经验的 暴饮暴食障碍风险的多因素模型考虑了三个因素 主要风险领域：家庭背景、体质脆弱性和 个人的脆弱。对于风险敞口的评估，数据将是 已被前瞻性地和纵向地收集了超过 在这个维护得特别好的队列中有十年的时间。我们会 检查种族差异在风险因素对 暴饮暴食障碍的发展；确定风险的特异性；以及 比较患有完全综合征的女性与患有全身性综合征的女性的风险暴露 谱系暴食症。我们的研究应该产生信息 通过识别高危人群和风险，与初级预防相关 可能会发生变化的因素。

DESCRIPTION (Adapted from the Applicant's Abstract): Eating disorders involving recurrent binge eating (binge eating disorders) pose a significant risk to the health and psychological adjustment of young women. Current knowledge of binge eating disorders is limited by a) the virtual exclusion of minority women from study samples; b) the paucity of studies of women with spectrum binge eating disorders; and c) the over reliance in risk factor studies on retrospective assessment of exposure to risk. As Aim I, the proposed study will assess a cohort of 2,379 young adult black and white women to describe the spectrum of binge eating disorders. Using state-of-the-art case finding interview methods, we will determine prevalence of bulimia nervosa (BN), binge eating disorder (BED), and their spectrum variants (defined as meeting all but one of the criteria required for full syndrome diagnosis); we will also identify presence of current Axis I psychiatric disorders. To determine clinical significance of BN, BED, and their spectrum variants in this community-based sample, we will compare women with a binge eating disorder and healthy controls on measures of obesity and psychological adjustment. The association of race and concomitant variables with eating disorder cases and controls will be examined. Aim II of the study is to develop an empirically based, multifactorial model of risk for binge eating disorders that considers three major risk domains: familial context, constitutional vulnerability, and personal vulnerability. For assessment of exposure to risk, data will be utilized that have been collected prospectively and longitudinally over a period of ten years in this exceptionally well-maintained cohort. We will examine race differences in the relative contribution of risk factors to the development of binge eating disorders; determine specificity of risk; and compare exposure to risk in women with full syndrome versus women with spectrum binge eating disorders. Our study should generate information relevant for primary prevention by identifying high risk groups and risk factors that may be amenable to change.