ION CHANNELS IN DROSOPHILA

研究建议：建议的研究是一系列优秀的 实验首先，评估磷酸化在调节中的作用 果蝇钠通道的功能，以及如何确定 果蝇神经元表达的离子通道的分子互补 单个神经元的聚合酶链式反应产物指纹图谱。这些研究 相辅相成：磷酸化和磷酸化的研究 果蝇对钠交替剪接域的调控 渠道是正在进行的研究的明确延伸，并利用 她熟悉的最先进的技术，例如单人- 细胞聚合酶链式反应，而最后一个具体目标包括 利用探索较少的技术，但可以提供重要的新技术 并为她提供继续进行研究的数据 在发育过程中离子通道表达的控制领域。

RESEARCH PROPOSED: The research proposed is an excellent series of experiments to first, evaluate the role of phosphorylation in regulating the function of drosophila sodium channels, and the to determine the complement of ion channels expressed by drosophila neurons by molecular fingerprinting of PCR products from single neurons. These studies complement each other well: the studies on phosphorylation and regulation of alternately spliced domains of drosophila para sodium channels are a clear extension of the ongoing research, and utilize state-of-the-art techniques with which she is familiar, such as single- cell PCR, while the last specific aim consists of experiments that utilize less explored techniques, but could provide significant new information and provide her with data that would continue her research in the area of control of ion channel expression during development.