How brains become lateralised

该项目旨在了解大脑的左右两侧如何专门用于不同的认知功能，这种现象称为侧化。侧化是最不为人所知的大脑组织原则之一，但对我们的思维和行为方式至关重要。最明显的表现是用手习惯，大脑在许多认知任务中是侧化的，如语言，推理，记忆和情感。然而，大多数认知不对称的发育起源和解剖学基础是未知的。该项目将使用一个小鸡大脑侧化模型来量化和定位特定的大脑回路，这些回路是导致解剖和功能不对称的差异基因表达模式。

This project aims to understand how the left and right sides of the brain become specialised for different cognitive functions, a phenomenon called lateralisation. Lateralisation is one of the least understood organisational principles of the brain, yet is crucial to the way we think and behave. Manifested most clearly as handedness, the brain is lateralised for many cognitive tasks such as language, reasoning, memory and emotion. However, the developmental origin and anatomical substrate of most cognitive asymmetries are unknown. This project will use a chick model of brain lateralisation to quantify and localise to specific brain circuits the patterns of differential gene expression that give rise to anatomical and functional asymmetries.