PEDIATRIC ONCOLOGY GROUP--MIDWEST CHILDREN'S CANCER CTR

中西部儿童癌症中心的主要目标是 减少儿童癌症的发病率和死亡率。这是 接洽方式：1)提供尽可能最好的病人护理(诊断 和治疗性；2)对医疗和非医疗团体进行关于 不同疾病的类型、治疗方法和可获得性 儿童癌症；3)临床和实验室研究。调查人员 癌症中心的专家包括儿科肿瘤学、外科、 整形外科，神经外科，放射学，放射治疗， 病理学、神经学、心理学和护理学。所有的新病人都是 在一个多学科肿瘤委员会上讨论过。然后孩子们就会 接受儿科肿瘤学小组(POG)或机构方案的治疗。 定期对结果进行分析和报告。 中西部儿童癌症中心参与的目的 POG是：L)提高实现上述目标的概率 通过与其他机构合作设计和执行 临床方案；2)通过实验室进行评估 肿瘤生物学方面的调查，这些方面导致成功和 治疗不成功。儿科肿瘤相对罕见。POG是 由50多个成员机构组成。通过汇集资源， 对这些罕见肿瘤的生物学和治疗研究如下 提供便利。类似的协作允许更快地开发新的 毒品。此外，在共同的环境中参与还能促进 在机构和调查人员之间传播信息。如果 所有患有癌症的儿童都得到了尽可能好的护理、发病率和 死亡率将降至最低。 中西部儿童癌症中心一直是POG的主要贡献者 通过：1)患者收益；2)POG方案的协调；3) 已进入POG研究的机构试点研究；以及4) 参加POG疾病和管理委员会。在下一个 在授权期内，我们将继续每一项活动。

The primary objective of the Midwest Children's Cancer Center is to reduce the incidence of and mortality from childhood cancers. This is approached by: 1) providing the best possible patient care (diagnostic and therapeutic; 2) education of medical and nonmedical groups as to the types of, treatments for, and availability of care for different childhood cancers; and 3) clinical and laboratory research. Investigators at the Cancer Center include specialists in pediatric oncology, surgery, orthopedic surgery, neurosurgery, radiology, radiation therapy, pathology, neurology, psychology and nursing. All new patients are discussed at a multidisciplinary Tumor Board. The children are then treated on Pediatric Oncology Group (POG) or institutional protocols. Results are analyzed and reported regularly. The purpose for the Midwest Children's Cancer Center's participation in POG are: l) to enhance the probability of achieving the above objectives by collaboration with other institutions in the design and execution of clinical protocols; and 2) to evaluate, through laboratory investigations, aspects of tumor biology which result in successful and unsuccessful therapy. Pediatric tumors are relatively rare. The POG is composed of more than 50 member institutions. By pooling resources, biologic and therapeutic studies on these uncommon tumors are facilitated. Similar collaboration permits more rapid development of new drugs. In addition, participation in a common milieu promotes dissemination of information between institutions and investigators. If all children with cancer receive the best possible care, morbidity and mortality will be minimized. The Midwest Children's Cancer Center has been a major contributor to POG by: 1) patient accrual; 2) coordination of POG protocols; 3) institutional pilot studies that were advanced to POG studies; and 4) participation in POG disease and administrative committees. In the next grant period we will continue each of these activities.