Evolution and specificity of alternative splicing in plants
Evolution and specificity of alternative splicing in plants
批准号:
DP190101479
负责人:
Prof Sureshkumar Balasubramanian
金额:
$29.5万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 2023-12-31
中文摘要
该项目旨在阐明选择性剪接的基本原理,这是一种在所有生物体的几种生物过程中起重要作用的基本机制。植物在适应不同的环境、季节和气候条件方面非常有效,本项目旨在揭示选择性剪接如何在响应发育和环境线索的过程中调节基因表达。揭示选择性剪接的潜在机制不仅将推进基础知识,而且有可能提供工具和技术,通过这些工具和技术,植物对环境胁迫的敏感性可以被潜在地操纵,从而有利于农业。
英文摘要
This project aims to elucidate fundamental principles of alternative splicing, a basic mechanism that plays a vital role in several biological processes across all organisms. Plants are highly effective in adapting to varied environmental, seasonal and climatic conditions and this project aims to uncover how alternative splicing contributes to regulation of gene expression in response to developmental and environmental cues. Uncovering the underlying mechanisms of alternative splicing will not only advance fundamental knowledge, but also has the potential to provide tools and technologies through which sensitivities of plants to environmental stress can be potentially manipulated to benefit agriculture.
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