BIOBEHAVIORAL IRREGULARITY AND CONTROL OF IDDM

产品说明： 这项为期三年的研究旨在检查胰岛素依赖型糖尿病 胰岛素依赖型糖尿病（IDDM）作为一种复发性功能障碍过程的发生器， 其特征在于包括失调的生物学和 行为因素、血糖（BG）不规则、严重低血糖 (SH)高糖化血红蛋白和不规则的生物行为 参数 这种跨学科的研究将创造个人评估 协议，先进的数据分析方法，易于阅读的标准化 生物和行为异常因素评价输出 与糖尿病有关。 第一阶段将重点关注生物和 行为因素，它们的相互作用和极端BG的贡献 不规则性 第二阶段将制定单独的方案， 失调因素，设计非标准高级数据分析 算法和软件。 第3阶段将使用数据验证这些协议 来自弗吉尼亚大学正在进行的研究，乔斯林糖尿病 中心和胰淀素制药公司

DESCRIPTION: The proposed three year study intends to examine Insulin Dependent Diabetes Mellitus (IDDM) as a generator of a recurrent dysfunction process that can be characterized by a loop that includes dysregulated biological and behavioral factors, blood glucose (BG) irregularity, severe hypoglycemia (SH) and high glycosylated hemoglobin, and irregular bio-behavioral parameters. This interdisciplinary study will create individual assessment protocols, advanced data analysis methods, and simple to read standardized output for evaluation of biological and behavioral irregularity factors associated with IDDM. Phase 1 will focus on modeling of biologic and behavioral factors, their interaction and contributions to extreme BG irregularity. Phase 2 will create individual protocols for assessment of dysregulated factors, designing non-standard advanced data analysis algorithms and software. Phase 3 will validate these protocols using data from ongoing studies at the University of Virginia, the Joslin Diabetes Center, and Amylin Pharmaceuticals.