APPARATUS FOR THE PREVENTION OF CATHETER INFECTIONS
APPARATUS FOR THE PREVENTION OF CATHETER INFECTIONS
批准号:
6073614
负责人:
ADRIAN J DENVIR
金额:
$10.52万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-05-01 至 2000-10-31
中文摘要
在美国,每年有2000万住院患者接受导尿术。与导管相关的感染与发病率增加、死亡率在10%至20%之间、延长住院时间以及增加每个患者数千美元的医疗费用有关。导尿管患者的皮肤是与导尿管感染相关的微生物的最常见来源。Lynntech Inc.开发了一种革命性的方法,可以制造微型臭氧发生器,用于以安全和受控的方式向特定皮肤区域供应测量剂量的臭氧气体。该装置包括微型臭氧发生器、流体管理系统、电源和必要的电子设备,尺寸将不超过一只手表,成本不到5美元。在第一阶段的研究中,我们将开发和建造一个完全封闭的臭氧装置,用于小试。第一阶段的可行性研究将证明,该装置可以成功地防止细菌迁移和防止导管污染。与抗生素粘合导管、镀银导管和磺胺嘧啶银溶液等其他治疗方法相比,扩展测试将显示该系统的长期益处。拟议的商业应用:正是这项技术的众多应用使其如此吸引人。这项技术不仅适用于导管感染的预防。有许多领域的感染预防,如烧伤伤口治疗和整形手术,将极大地受益于该产品。
英文摘要
In the United States each year 20 million hospital patients are catheterized. Catheter related infections are associated with increased morbidity, mortality rates of between 10% and 20%, prolonged hospitalization, and increased medical costs of thousands of dollars per patient. The skin of a catheterized patient is the most common source for the microorganisms that are associated with catheter infections. Lynntech Inc has developed a revolutionary method of making miniaturized ozone generators that can be used to supply a measured dose of ozone gas to a specific area of skin in a safe and controlled manner. The unit, containing the micro ozone generator, fluid management system, power supply, and necessary electronics, will have dimensions no larger than a wrist watch, and cost less than $5. During the Phase I research, we will develop and build a fully contained ozonation unit for bench scale testing. The Phase I feasibility study will demonstrate that the unit can be used to successfully prevent bacteria migration and prevent catheter contamination. Extended testing will show the long term benefits of the system when compared to other treatments such as antibiotic bonded catheters, silver coated catheters, and silver-sulfadiazine solution. PROPOSED COMMERCIAL APPLICATIONS: It is the many applications of this technology that make it so attractive. This technology is not just applicable to catheter infection prevention. There are many areas of infection prevention such as burn wound treatment and plastic surgery that would benefit greatly from this product.
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