SNI-2011 TO TREAT PATIENTS WITH SJOGREN'S SYNDROME

干燥综合征是一种免疫性疾病， 和口干，包括腺体分泌减少或缺乏， 组织. SNI-2011是乙酰胆碱的奎宁环衍生物， 与改善的腺体增加的能力相关的毒蕈碱激动剂 流涎和流泪。 这项研究将比较两种药物的疗效。 SNI-2011（15 mg和30 mg tid）与安慰剂联合给药， 干燥的主观总体评价（口腔、眼睛和整体）。

Sjogren's syndrome is an immunological disorder characterized by dry eyes and dry mouth, which includes diminished or absent secretion of glandular tissue. SNI-2011, a quinuclidine derivative of acetylcholine, is a muscarinic agonist associated with improved glandular ability to increase salivation and lacrimation. This study will compare the efficacy of two doses of SNI-2011 (15 mg and 30 mg tid) with placebo on the patients' subjective global evaluation of dryness (mouth, eyes, and overall).