CLINICAL NEUROSCIENCE MENTAL HEALTH RESEARCH TRAINING

神经科学研究的进步使发现许多精神疾病的生物病因和发病机制成为现实，这反过来将为开发改进的治疗方法、预防疾病和治愈患者提供主要途径。我们的目标是构建一个培训计划，吸引和吸引医学生、研究生、博士后研究员和精神病学住院医生从事翻译临床神经科学研究职业，在这些职业中，他们将把基础神经科学知识应用于精神病学的临床研究。该计划将由两部分组成：1)以现代精神病学为导向的教学课程，将基础和临床神经科学与临床精神病学相结合；2)全日制，12个月结构和指导的临床神经科学研究培训经验。该课程的特点是跨学科整合，重点是了解精神疾病。将使用病例报告、现场采访和视频剪辑来说明基础神经科学各个方面的临床相关性。每年，该课程的核心内容将以互动讲座的形式向200名一年级和二年级医学生、30名研究生、17名精神科住院医生和35名博士后研究员介绍。该计划的一个新颖和独特的方面是开发和使用广泛的互动电子教学大纲，涵盖课程的所有方面(即通过计算机访问参考文献摘要和额外阅读资料的全文、互动图形、动画、录制患者陈述的视频，以及自学和自我评估的机会)。这将在耶鲁大学的内联网上提供给所有参加讲座的学生、住院医生和研究员。该计划的一个关键方面是，选定的个人有机会选择12个月的结构化和有指导的临床研究培训经验，在那里，他们将在自己进行临床神经科学研究的高级研究人员的监督下，接受特定临床研究方法的培训。教学课程和指导的临床研究经验将特别为参与者的教育水平和经验量身定做。整个计划将建立评估方法，并每年进行跟踪。该方案的各个方面将作为可能在国家一级使用的范本提供。

Advances from neuroscience research now make it realistically possible to discover the biologic causes and pathogenesis of many psychiatric illnesses, and this in turn will provide the major avenues for developing improved treatments, prevention of illness, and cure of patients. Our goal is to construct a training program that will attract and engage medical students, graduate students, postdoctoral fellows, and psychiatric residents in translational clinical neuroscience research careers where they will apply knowledge from basic neuroscience to clinical research in psychiatry. The program will consist of two componets: 1) a modern psychiatry oriented didactic curriculum which integrates basic and clinical neuroscience with clinical psychiatry and, 2) full-time 12 month structured and mentored clinical neuroscience research training experiences. The curriculum is distinguished by its integration across disciplines with a focus on understanding psychiatric illness. Case reports, live interviews, and video clips will be used to illustrate the clinical relevance of each aspect of basic neuroscience. Each year core aspects of the curriculum will be presented in an interactive lecture format to 200 1st and 2nd year medical students, 30 graduate students, 17 psychiatric residents and 35 postdoctoral fellows. A novel and unique aspect of the program is the development and use of an extensive interactive electronic syllabus covering all facets of the curriculum (i.e. full text with computer access to abstracts of references and additional readings, interactive graphics, animation, video taped patient presentations, and opportunities for self study and self evaluation). This will be available on a Yale University Intranet to all students, residents, and fellows who attend the lectures. A key aspect of the program is the opportunity for selected individuals to elect a 12 month structured and mentored clinical research training experience where they will receive training in specific clinical research methods under the supervision of senior investigators who are themselves conducting clinical neuroscience research. The didactic curriculum and the mentored clinical research experiences will be specifically tailored to the educational level and experience of the participants. The entire program will have built in methods for evaluation with yearly follow up. Aspects of this Program will be available as a model for possible utilization at the national level.