NEUROSCIENCE TRAINING PROGRAM

这是一个新的申请，要求资金支持两年广泛的神经科学博士前培训。该培训计划强调多学科方向，并以NINDS的使命为指导，促进神经系统疾病的预防、诊断和治疗工作，以及为此目的的基础科学。该计划借鉴了在基础和临床部门担任主要职务的科学家之间密切互动的悠久传统，以及他们在基础和临床研究之间的相互作用方面对学生进行正式和实例指导的可能性。导师包括30名外部资助的神经科学家，他们的研究兴趣集中在离子通道的生物物理和药理学特性；正常、发育和病理状态下的突触蛋白和信号分子；心血管和自主调节；内脏疼痛机制；神经肌肉疾病;细胞和系统水平的皮层和皮层下组织；自闭症、抑郁症和精神分裂症的神经生物学；痴呆的诊断与治疗；以及高级认知过程（感知、记忆、语言、情感和决策）的神经心理学和解剖学。更大的教师队伍参与神经科学项目的教学、委员会工作和其他活动，并可以作为学生的共同导师。神经科学培训计划强调学生在一系列分支学科中获得经验，使他们能够在快速发展的多学科学术环境中有效地发挥作用。学生将在五个细分领域（细胞神经科学、发育神经科学、分子神经科学、系统神经科学和行为神经科学）内进行课程学习和实验室轮转。这种结构也作为专题综合系列讨论会和期刊俱乐部的基础。在第二年末有一个两部分的书面和口头综合考试，随后的几年主要用于论文研究。目前申请的助学金用于支持学生在第一年和/或第二年，在他们致力于特定的研究方向之前。

This is a new application requesting funds to support two years of broad predoctoral training in Neurosciences. This Training Program emphasizes a multi-disciplinary orientation, and is guided by the NINDS mission to foster work toward the prevention, diagnosis, and treatment of nervous system disorders and the basic sciences fundamental to this purpose. The Program draws on a long tradition of close interactions among scientists with primary appointments in basic and clinical department, and their availability to instruct students, both formally and by example, in the interplay between basic and clinical research. Mentors include 30 extramurally-funded neuroscientists with research interests focused on biophysical and pharmacological properties of ion channels; synaptic proteins and signaling molecules in normal, developmental, and pathological states; cardiovascular and autonomic regulation; visceral pain mechanisms; neuromuscular diseases; cortical and subcortical organization at a cellular and systems level; neurobiology of autism, depression, and schizophrenia; diagnosis and treatment of the dementias; and the neuropsychology and anatomy of higher cognitive processes (perception, memory, language, emotion, and decision making). A larger faculty pool participates in teaching, committee work, and other activities on the Neuroscience Program, and can serve as co-mentors for students. The Neuroscience Training Program emphasizes that students gain experience in a range of subdisciplines, to allow them to function effectively in a rapidly evolving multi-disciplinary academic environment. Students take a combination of coursework and laboratory rotations, organized within the structure of five subdivisions (cellular, developmental, molecular, systems, and behavioral neuroscience). This structure also serves as the basis for a thematically integrated seminar series and journal clubs. There is a two-part written and oral Comprehensive Exam at the end of the second year, with subsequent years devoted primarily to thesis research. Stipends from the present application are mentation to support students in their first and/or second year, prior to their commitment to a specific research direction.