INFECTION CONTROL IN GENE THERAPY

描述(申请人的描述) 基因疗法正在研究中，用于治疗各种各样的获得性 和遗传性疾病。逆转录病毒，腺病毒，痘病毒， 腺相关病毒、疱疹病毒和其他病毒正在被改造成 将基因转移到人类体内。使用重组病毒的治疗方案是 被引入到临床环境中。感染控制从业者将 总是参与审查这些代理人在他们的 诊所和医院。到目前为止，还没有广泛可用的建议。 来自联邦或私人组织，以指导感染控制从业者- 内斯。本次会议旨在为基因治疗专家提供一个论坛。 分享他们对感染控制的看法和经验 希望从事临床基因治疗的从业者和其他人 协议。主题将包括但不限于管理 患者志愿者在门诊和住院环境中，设施设计， 医护人员的安全，药房对媒介生物的处理， 内务和消毒，事故应急反应，协调 与包括公共卫生部门在内的外部医疗机构合作，以及 家庭成员和其他密切接触者的安全。世界银行的目标是 会议的目的是提供一个论坛，让基因治疗专家们聚集在一起 一起分享他们对感染控制的看法和经验 基因疗法，并为该领域的新手提供机会 了解基因治疗中感染控制的具体问题。这次会议 将于1999年10月22日至23日在列克星敦万豪酒店举行， 肯塔基州。

DESCRIPTION (Applicant's Description) Gene therapy is being studied for the treatment of a wide variety of acquired and inherited disorders. Retroviruses, adenoviruses, poxviruses, adeno-associated viruses, herpesviruses and others are being engineered to transfer genes into humans. Treatment protocols using recombinant viruses are being introduced into clinical settings. Infection control practitioners will invariably be involved in reviewing the safety of these agents in their clinics and hospitals. To date, no widely available recommendations exist from federal or private organizations to guide infection control practitio- ners. This conference is designed to provide a forum for gene therapy experts to share their perspectives and experiences with infection control practitioners and others who wish to engage in clinical gene therapy protocols. Topics will include, but are not limited to, the management of patient volunteers in the ambulatory and inpatient setting, facility design, safety of healthcare workers, handling of vectors by the pharmacy, housekeeping and disinfection, emergency response to accidents, coordination with outside healthcare facilities including Public Health Departments, and safety for family members and other close contacts. The goals of the conference are to 1) provide a forum where gene therapy experts can gather together to share their perspectives and experience with infection control in gene therapy, and to 2) provide an opportunity for newcomers to the field to learn about issues specific to infection control in gene therapy. The meeting will be held on October 22-23, 1999 at the Marriott Hotel in Lexington, Kentucky.