CELL CONTACT AND ADHESION GORDON CONFERENCE

资金要求支持戈登会议细胞接触和粘附。该会议自1973年以来每隔一年召开一次，是该领域的重要会议之一。会议旨在以一种非常有利于正式和非正式交流的形式将各种科学家聚集在一起。此外，会议为那些在该地区开始职业生涯的人提供了一个极好的教育机会。选定的发言者不仅代表一些最活跃的团体，而且也代表有能力就其本身和其他主题进行有益讨论的个人。会议强调最近取得进展的领域，并对包括分子生物学家，细胞生物学家，发育生物学家，神经生物学家和癌症生物学家在内的各种科学家感兴趣。会议将围绕几个生物学问题或主题组织。其中一个主题是神经元连接的建立，这对我们对细胞-细胞识别的一般理解有重大贡献，而细胞-细胞识别与细胞粘附和形态发生的其他领域高度相关。关于粘附接触的结构，机制和调节的主要会议将有助于我们理解细胞接触的动态变化，这些变化是许多与癌症和发展相关的形态发生过程的基础，包括细胞迁移，细胞重排和细胞侵袭。另一个主要会议将提供一个机会，讨论粘附受体和细胞连接蛋白如何与信号转导通路，控制细胞生长和分化的胚胎和肿瘤细胞，血管生成和细胞侵袭力。此外，会议将举行，以解决如何粘附和连接蛋白有助于组织形态发生在一些不同的生物系统（神经系统外）的更大的问题。还将举行一次从摘要中选出的会谈，以便为有前途的年轻研究人员提供一个介绍他们最近研究结果的机会。本次会议旨在汇集一群具有不同系统和方法的科学家和学生，以更全面地了解细胞粘附和形态发生的共同主题。

Funds are requested to support the Gordon Conference on Cell Contact and Adhesion. This conference has convened every other year since 1973, and represents one of the key meetings in the field. The conference is intended to bring together a diversity of scientists in a format highly conducive to both formal and informal exchange. In addition, the meeting provides an excellent educational opportunity for those who are beginning their careers in the area. The speakers chosen represent not only some of the most active groups, but also individuals with the capacity to generate useful discussion of their own and other topics. The sessions emphasize areas of recent progress, and are of interest to a diverse community of scientists including molecular biologists, cell biologists, developmental biologists, neurobiologists, and cancer biologists. The conference will be organized around several biological problems or themes. One such theme, the establishment of neuronal connections, is contributing significantly to our general understanding of cell-cell recognition, which is highly relevant to other areas of cell adhesion and morphogenesis. A major session on the structure, mechanisms, and regulation of adhesive contacts will contribute to our understanding of the dynamic changes in cell contacts that underlie many morphogenetic process relevant to cancer and development, including cell migration, cell rearrangement, and cell invasion. Another major session will provide an opportunity to discuss how adhesion receptors and cell junction proteins interact with signal transduction pathways that control cell growth and differentiation in embryos and in tumor cells, angiogenesis, and cell invasiveness. Also, a session will be held to address how adhesion and junctional proteins contribute to the larger problem of tissue morphogenesis in a number of different biological systems (outside the nervous system). A session of talks chosen from abstracts will also be held in order to provide an opportunity for promising young investigators to present their recent findings. This conference aims to bring together a group of scientists and students with diverse systems and approaches to allow more complete understanding of the common themes of cell adhesion and morphogenesis.