FLORIDA A&M UNIVERSITY RESEARCH CENTER

长期目标：建立高水平的竞争力 医药研究。具体目标：提高教师和学生的素质 对提案准备的理解和能力；加强 图书馆藏书以支持博士跟踪和药理学研究/ 毒理学、药物化学和环境毒理学；增加 动物饲养空间；为新聘用的教师提供基础支持 培训少数族裔获得药学博士、药学博士、DVM和医学博士学位- 药物研究；开发新的有效和安全的药物；以及研究 某些疾病状态下的民族药理现象。方法：研究方法。这个 行政基础设施将确定融资机会，提供 对统计、编辑、图形和文字处理的支持，以及两者 对建议书进行内部和外部审查。一份提案准备和 格兰特管理课程和最先进的研究研讨会系列 将会建立起来。基本文本和补充文本将确保 加强图书馆研究。光盘MEDLINE、DIALOG和国家图书馆 将提供医学在线搜索功能。最先进的 笼子里可以关老鼠和老鼠。面向新研究的基础科学和 临床药学教师方案将根据以下优点进行评估 对基础通用设备的要求。少数民族健康 理科博士学位获得者将在 药学研究的进行。新药将被合成并 进行了筛选以确定活动情况。中国民族差异产生的基础 止痛药的药代动力学和药效学研究 老年非裔美国人和西班牙裔美国人的癌症和高血压药物 将会被研究。限制片段长度多态技术将 用于阐明药物种族差异的分子基础 回应。

Long term objective: to establish a high level of competitiveness in pharmaceutical research. Specific aims: enhance faculty and student understanding- of, and capability in, proposal preparation; strengthen library holdings to support PhD tracks and research in pharmacology/ toxicology, medicinal chemistry and environmental toxicology; increase animal holding space; provide foundational support for newly hired faculty train minority recipients of PhD, PharmD, DVM, and MD degrees in pharma- ceutical research; develop new potent and safe drugs; and to investigate ethnopharmacological phenomena in certain disease states. Methods. The administrative infrastructure will identify funding opportunities, provide statistical, editorial, graphics, and word processing support, and both internal and external review for proposals. A proposal preparation and grant administration course and a state-of-the-art research seminar series will be established. Basic and supplementary text will be secured to enhance library research. CD-ROM MEDLINE, DIALOG, and National Library of Medicine on-line search capabilities will be provided. State-of-the-art cages will house mice and rats. New research oriented basic science and clinical pharmacy faculty protocols will be evaluated for the merit of requests for foundational general purpose equipment. Minority health science doctoral degree recipients will receive experience and guidance in the conduct of pharmaceutical research. New drugs will be synthesized and screened to determine activity. The bases for ethnic differences in the pharmacokinetics and pharmacodynamics of analgesics, drugs used to treat cancer, and hypertensive agents in elderly African-American and Hispanics will be studied. Restriction fragment length polymorphism techniques will be used to elucidate the molecular basis for ethnic differences in drug response.