ANIMAL RESOURCE IMPROVEMENT - MGH

需要资金来改善动物收容所和研究设施 并全面实施中央动物护理资源计划 马萨诸塞州综合医院通过扩建设施来满足增加 动物研究需求和提高获取AAALAC的能力 认证。玛嘉烈医院是内科医生的主要教学医院。 以及其他生物医学研究科学家，这取决于可用性 来支持他们的研究。越直接越好 这项提议的目标是为正在进行的研究提供支持 实验外科、细胞生物学、创伤和内分泌学。长期的 目标是允许分子研究领域有计划的增长 生物学、免疫学、癌症、受体和激素代谢、皮肤 生物学、器官移植和免疫学、磁共振成像 和激光技术研究。具体地说，请求提供支持以 翻新和升级三个动物室，一个办公室，一个接待室和 在主要医院的场地上有一个食物和床上用品储藏室。这些 翻新将提供更多的狗、灵长类动物和农场动物收容 太空。查尔斯敦海军LEM实验室设施的重大翻新 院子(约250,000平方英尺)需要满足目前和 建议增加该网站的研究项目。设备是 要求提供翻新的设施和更换破旧和 设备陈旧，不符合现行标准。MGH希望 为动物研究相关项目提供的资金将超过4000万美元 到1992年，基于已经批准的资助和/或合理的项目 保证得到资助。其中很大一部分资金是 来自小灵通来源的预期。这家医院已经花费了超过6.5美元 在过去五年内，为确保人员、设备、 设施翻新和建设。预计MGH将扩大支出 超过250万美元用于在未来几年内改善动物资源 三到五年。重要的是医院的动物资源 该计划通过AAALAC认证，以展示 致力于保持高质量的项目。批准和资助这一项目 如果MGH要实现这一目标，建议是必不可少的。

Funds are requested to improve the animal housing and research facilities and fully implement a centralized animal care resource program at the Massachusetts General Hospital by expansion of facilities to meet increased animal research demand and to enhance ability to obtain AAALAC accreditation. The MGH serves as a major teaching hospital for physicians and other biomedical research scientists that depends on the availability of quality research animals to support their research. The more immediate goal of this proposal is to provide support for the ongoing research in experimental surgery, cell biology, trauma and endocrinology. The long-term objectives are to allow for planned growth in research areas of molecular biology, immunology, cancer, receptor and hormone metabolism, cutaneous biology, organ transplantation and immunology, magnetic resonance imaging and laser technology research. Specifically, support is requested to renovate and upgrade three animal rooms, one office, one receiving room and one food and bedding storage room on the main hospital grounds. These renovations will provide additional dog, primate and farm animal holding space. Major renovations of the LEM Lab facility at the Charlestown Navy Yard (approximately 250,000 square feet) are required to meet present and proposed increases in research programs at that site. Equipment is requested to furnish renovated facilities and replace dilapidated and outdated equipment which does not meet current standards. The MGH expects funding for animal research-related projects to exceed 40 million dollars by 1992 based upon projects already approved for funding and/or reasonably assured of being funded. A significant portion of the funding is anticipated from PHS sources. The Hospital has expended in excess of $6.5 million within the past five years to secure personnel , equipment, facility renovations and construction. It is expected that MGH will expend more than $2.5 million toward animal resource improvements within the next three to five years. It is important that the Hospital's animal-resource program achieves AAALAC accreditation in order to demonstrate the commitment to maintain a quality program. Approval and funding of this proposal is essential if the MGH is to accomplish this goal.