RENOVATION OF THE EK SHRIVER ANIMAL FACILITY

鉴于实验动物模型的日益重要性， 在人类神经系统疾病的研究中， 中心已经开始了一项发展计划，将扩大范围， 在校园里进行的动物相关研究的范围。 我们的前锋 规划过程已经确定了当前动物的几个关键特征， 需要升级的设施，以跟上这一步伐 预期增长。 本提案载有我们解决这一问题的计划 问题. 当拟议的翻修完成后，该中心的动物 住房将有一个完全翻新的笼子清洗设施， 用更大的直通式洗衣机取代现有的单门洗衣机; a 还将增加直通灭菌器。 HVAC系统将 完全改造和升级为一个独立的系统， 不依赖其他非动物专用设备进行加热、冷却或 通风. 这些措施的实施将使两条走廊 建立畜牧业生产体系。 最后，新的变化 将通过安装紧急保护装置， 生成器. 这些变化将共同建立一个环境， 传染源的传播可以得到控制， 所有动物的健康状况都得到了显著改善。 此外，由 提前规划，我们的目标是确保动物设施的 施莱佛中心可以跟上动物相关研究的发展步伐 并继续达到AAALAC规定的最高标准 指南，DHHS政策和美国农业部动物福利法案。

In recognition of the increasing prominence of experimental animal models in the study of human neurological disease, the Eunice Kennedy Shriver Center has begun a program of development that will expand the range and scope of animal relates research that is conducted on campus. Our forward planning process has identified several key features of the current animal facility that need to be upgraded for the facility to keep pace with this anticipated growth. This proposal contains our plans to address this issue. When the proposed renovations are completed, the Center's animal housing will have a completely renovated cage washing facility that will replace the current singledoor washer with a larger, pass-through type; a pass-through sterilizer will also be added. The HVAC system will be completely re-vamped and upgraded to a single independent system that does not rely on other non-animal dedicated equipment for heating, cooling or ventilation. Institution of these measures will allow a two-corridor system of animal husbandry will be established. Finally, the new changes will be protected from power outages by installation of an emergency generator. Together, the changes will establish an environment in which the entry and spread of infectious agents can be controlled, and the health and safety of all animals in the facility significantly improved. Further, by planning ahead, it is our goal to ensure that the animal facility of the Shriver Center can keep pace with the growth of animal related research and continue to meet the highest standards set forth by the AAALAC guidelines, by DHHS policies, and by the USDA Animal Welfare ACT.