TMD LONGITUDINAL STUDIES: CLINICAL/CHRONIC PAIN SYNDROME

TMD纵向研究：临床/慢性疼痛 综合征，建议启动一个系统的计划， 多学科研究调查发病，临床过程， 颞下颌关节疼痛和功能障碍的自然史和预防 （TMD）。 TMD是指一系列以疼痛为特征的疾病， 咀嚼肌和/或颞下颌关节、下颌 功能障碍和关节音 拟议的计划项目涉及两个持续的合作 机构：华盛顿大学口腔医学系， 牙科学院和普吉特海湾团体健康合作社（中心 健康研究）。 在早期的研究活动中， 临床，行为和流行病学研究人员已经开发 以及训练有素的技术人员。 的具体目标 方案项目有：1.（a）继续先前的纵向研究 确定关键的生物、心理和人口因素 影响TMD的发病、临床病程和自然史， 亚型;和B）评估TMD体征和症状的自然史， 最初没有TMD的人（项目1）。 2.进行纵向 调查慢性疾病的性质、发生和后果的研究 疼痛综合征（项目2）。 3.调查牙医知识的变异性 生物、心理和社会心理因素的水平和理解 影响TMD和其他慢性疼痛的发展和管理 条件（项目3）。 4.为了评估早期生物行为治疗的有效性， 用于改善和预防慢性疼痛的干预和慢性疼痛 综合征（项目4）。 5.为了支持这些研究目标， 科学和行政核心项目， 计划项目的沟通、技术和支持能力 investigators. 这个基础广泛的疼痛研究项目将提高牙医的能力 和医生提供更有效的诊断和治疗TMD 并预防慢性TMD疼痛最具破坏性的后遗症。

A Program Project, TMD LONGITUDINAL STUDIES: CLINICAL/CHRONIC PAIN SYNDROMES, is proposed to initiate a systematic program of multidisciplinary research investigating the onset, clinical course, natural history and prevention of temporomandibular pain and dysfunction (TMD). TMD refers to a range of disorders characterized by pain in the muscles of mastication and/or the temporomandibular joint, mandibular dysfunction, and joint sounds. The proposed Program Project involves the continued collaboration of two institutions: the University of Washington Department of Oral Medicine, School of Dentistry, and Group Health Cooperative of Puget Sound (Center for Health Studies). Under earlier research activity a cohesive team of clinical, behavioral, and epidemiologic researchers has been developed together with a uniquely trained technical staff. The specific aims of the Program Project are: 1. a) To continue prior longitudinal research identifying critical biologic, psychologic and demographic factors influencing the onset, clinical course and natural history of TMD and its subtypes; and b) to assess the natural history of TMD signs and symptoms in persons initially free of TMD (Project 1). 2. To conduct longitudinal studies investigating the nature, occurrence and consequences of a chronic pain syndrome (Project 2). 3. To survey dentists variability in knowledge levels and understanding of biologic, psychologic and psychosocial factors influencing the development and management of TMD and other chronic pain conditions (Project 3). 4. To evaluate the efficacy of early biobehavioral interventions for ameliorating and preventing chronic pain and chronic pain syndrome (Project 4). 5. To support these research objectives through scientific and administrative Core projects providing centralized communication, technical, and support capabilities for Program Project investigators. This broad-based pain research project will enhance the ability of dentists and physicians to provide more effective diagnosis and treatment for TMD and to prevent the most devastating sequelae of chronic TMD pain.