Biochemical Engineering MSc

UCL生物化学工程硕士的目标是更好地使英国公司能够获得与知识密集型，高科技（生物）制造相关的附加值。我们专门解决在最近的BIGT，ABPI和IB-IGT报告中确定的实际生物工艺技能需求，并强调工业生物技术和具有成本效益的全球医疗保健提供的新机遇和生物工艺挑战。现有的课程在提供高质量的跨学科研究生教育方面有着良好的记录。新的硕士课程将在此基础上提供两个流，一个为生物科学或化学毕业生，另一个为工程毕业生。这两个流的学生将接受培训，以了解如何在生命科学和化学的进步可以最有效地转化为造福所有人的真实的成果。与生物化学工程高级中心（ACBE）的研究活动密切联系，确保培训围绕最新的科学发现和生物加工技术进行。新的微型生物化学工程和建模方法，以缩小规模的实验，现在正在采取由我们的工业合作者，提供了基础上，学生可以探索一系列新兴的生物过程的挑战，并建立规模扩大的预测，以验证在我们独特的中试工厂设施。硕士课程的内容将大大受益于与该部门的岗位经验MBI培训计划的联系，其中约80名工业专家与硕士学生一起帮助向工业代表提供服务。新方案将分为四个不同但相关的部分。1)转换元素（45学分）-生物化学工程基础（理科毕业生）。提供与生物材料处理相关的过程工程基础知识，以及描述生物系统的数值技术应用。- 高级生命科学（工程专业毕业生）。提供对细胞和蛋白质功能及其分子工程或进化的见解，以提高效率和生物过程性能。2)高级生物化学工程和生物过程实施（60学分）这些核心要素将教授生物基制造的设计，即发酵和生物转化，随后的回收，纯化和产品配方。这将得到一系列关于单个单元操作的实验的支持。新的微型生物化学方法将扩大学生的实践知识。所获得的信息将导致研究/设计项目，并在为期一周的整个生物工艺研究在该部门的试点工厂设施的实验验证。3)研究或设计项目（45学分）上述要素在前8个月内同时完成，以便获得的技能可以应用于设计或研究项目。- 生物工艺设计项目对于希望获得特许工程师身份的研究生科学家来说，这是该计划的重要组成部分。它涉及生物过程的完整设计，以及经济和安全分析以及验证考虑。2009年，该项目审查了大流行性流感疫苗的要求。- 生物过程研究项目每个候选人进行自己选择的原创研究项目，在学术人员的监督下。学生完全融入ACBE内的多学科研究团队之一。主题范围从化学-酶促合成到治疗性抗体和干细胞生物加工。4)生物工艺风险管理（30学分）这一要素认识到新产品和工艺的发现往往是由小型高科技公司推动的。它集中在生产和生物工艺业务计划的介绍。

The objective of the UCL Biochemical Engineering MSc is to better enable UK companies to capture the added value associated with knowledge-intensive, high-technology (bio)manufacture. We specifically address practical bioprocess skills needs identified in recent BIGT, ABPI and IB-IGT reports and highlight new opportunities and bioprocess challenges in Industrial Biotechnology and cost-effective global healthcare provision. The existing course has a proven track record of providing high quality interdisciplinary postgraduate education. The new MSc programme will build on this to offer two streams, one for bioscience or chemistry graduates and the other for engineering graduates. Students on both streams will be trained to understand how advances in the life sciences and chemistry can most effectively be translated into real outcomes of benefit to all. Close linkage to the research activities of The Advanced Centre for Biochemical Engineering (ACBE) ensures that training is built around the latest scientific discoveries and bioprocessing technologies. New micro biochemical engineering and modelling approaches to scale-down experimentation, now being taken up by our industrial collaborators, provide the basis on which students can explore a range of emerging bioprocess challenges and establish scale-up predictions to be verified in our unique pilot plant facilities. The content of the MSc programmes will benefit considerably from linkage to the department's post experience MBI Training Programme, in which some 80 industrial experts help deliver to industrial delegates, alongside MSc students. The new programme will be divided into four distinct but related elements. 1) CONVERSION ELEMENTS (45 Credits) - Biochemical Engineering Fundamentals (for science graduates). To provide the fundamentals of process engineering relevant to the handling of biological materials and the application of numerical techniques to describe biological systems. - Advanced Life Sciences (for engineering graduates). To provide insights into the function of cells and proteins and their molecular engineering or evolution to enhance efficency and bioprocess performance. 2) ADVANCED BIOCHEMICAL ENGINEERING & BIOPROCESS IMPLEMENTATION (60 Credits) These core elements will teach the design of bio-based manufacturing, i.e. fermentation & biotransformation, subsequent recovery, purification and formulation of products. This will be supported by a series of experiments on individual unit operations. New micro biochemical approaches to scale-down will broaden the student's practical knowledge. Information obtained will lead into research/design projects and be verified experimentally during week-long whole bioprocess studies in the department's pilot plant facility. 3) RESEARCH OR DESIGN PROJECT (45 Credits) The elements above are completed concurrently in the first 8 months so that the skills gained may be applied to either a design or research project. - Bioprocess Design Project For graduate scientists wishing to obtain Chartered Engineer status this is a vital part of the programme. It involves the complete design of a bioprocess, together with economic and safety analyses, and validation considerations. In 2009 the project examined the requirements for a pandemic flu vaccine. - Bioprocess Research Project Each candidate carries out an original research project of their choice, under the supervision of a member of academic staff. The students are fully integrated into one of the multidisciplinary research teams within the ACBE. Topics range from chemo-enzymatic synthesis to therapeutic antibody and stem cell bioprocessing. 4) MANAGEMENT OF BIOPROCESS VENTURES (30 Credits) This element recognises that discovery of new products and processes is often driven by small, high-tech companies. It is centred on production and presentation of a bioprocess business plan.