EPIDEMIOLOGY OF TUMORS OF THE PAROTID GLAND

我们提出了一项病例对照研究，以检验以前接触过的 诊断性牙科X光和其他形式的辐射与 腮腺肿瘤。我们还将评估其他因素的重要性 这种疾病的潜在危险因素。 病例包括所有类型的腮腺肿瘤(包括良性和恶性)。 由LAC/南加州大学癌症监测计划在五年内确定的。 控制相同性别、种族和年龄(出生年份在五年内)的邻居将 为每种情况选择。有关牙科和医用X光、工作的信息 暴露、家族癌症和烟酒使用将通过以下途径获得 使用标准问卷进行电话采访。采访信息： 牙科X光将通过审查对病例和对照的子集进行验证 牙科记录。 不同年龄段的各种接触的相对重要性将是 已评估。肿瘤的发生与辐射暴露和 不同组织学肿瘤的吸烟史将分别进行分析 类型。

We propose a case-control study to test the hypothesis that previous exposure to diagnostic dental X-rays and to other forms of radiation are causally related to tumors of the parotid gland. We will also evaluate the importance of other potential risk factors for this disease. Cases include all types of parotid neoplasms (both benign and malignant) identified by the LAC/USC Cancer Surveillance Program over a five year period. A neighbor control of like sex, race and age (birth year within five years) will be selected for each case. Information on dental and medical X-rays, job exposures, family cancers and tobacco and alcohol use will be obtained through telephone interviews using a standard questionnaire. Interview information on dental X-rays will be validated for a subset of cases and controls by a review of dental record. The relative importance of various exposures at different ages will be evaluated. Associations of tumor occurrence with radiation exposure and with smoking history will be analyzed separately for tumors of different histologic types.