A STUDY OF AGE-RELATED DIFFERENCES IN CANCER MANAGEMENT

该研究项目旨在评估 在患者方面区分老年患者和年轻患者 管理程序已被证明可以降低发病率， 女性乳腺癌和直肠癌死亡率。 鉴于 年轻的白色乳腺癌患者在1，3 或5年相对生存率，并考虑到 年轻的白色女性直肠癌患者经历15%至20%的 与老年患者相比，1年、3年和5年相对生存率较高， 的系统性差异可能存在， 提供给和/或 直肠癌的女性接受，这可能不存在或存在于一个 乳腺癌的程度较低。 鉴于这两种疾病的发病率都在上升 老年人中的癌症，以及年龄似乎扮演的不同角色， 对于两个网站之间的生存，这是非常重要的， 了解患者管理和行为因素的影响， 关系到疾病和宿主的特点，有对模式的照顾 用于中老年女性癌症患者的特定人群。 纪念斯隆-凯特琳癌症中心与新 约克州卫生部、康奈尔大学医学中心和 国家意见研究中心建议通过以下方式评估这些问题： 鉴定纽约市白色女性患者的代表性样品， 45岁及以上，患有乳腺癌或直肠癌， 患者和每个患者指定的支持人员，获得临床 来自患者病历和患者医生的数据 并分析这些数据以确定年龄变量的影响， 社会经济状况和疾病部位对治疗前选择的影响， 由医生提供并由医生选择的治疗选择和后续护理 病人

This research project has been designed to evaluate factors that differentiate older from younger patient groups in terms of patient management procedures that have been shown to reduce the morbidity and mortality from breast cancer and rectal cancer in females. Given that younger white breast cancer patients do not experience differences in 1, 3 or 5 year relative survival compared with older age groups, and given that younger white female rectal cancer patients experience between 15 and 20% higher 1, 3, and 5 year relative survival compared with older patients, it is suggested that systematic differences may exist in prognostically significant patient management procedures, that are offered to and/or accepted by women with rectal cancer, which may not exist or exist to a lesser extent for breast cancer. Given the increased incidence of both cancers among the elderly, and the different role age seems to play with respect to survival between the two sites, it is extremely important to understand the impact that patient management and behavioral factors, in relation to disease and host characteristics, have on the patterns of care for a defined population of middle-aged and elderly female cancer patients. The Memorial Sloan-Kettering Cancer Center in collaboration with the New York State Department of Health, Cornell University Medical Center and the National Opinion Research Center, proposes to evaluate these issues by identifying a representative sample of New York City white female patients, 45 and older, with cancers of the breast or rectum, interviewing these patients and a support person named by each patient, obtaining clinical data from the patients' medical records and from the patients' physicians and analyzing these data to determine the effects of the variables of age, socio-economic status and site of disease on pre-treatment choices, treatment choices and follow-up care offered by the physician and chosen by the patient.