Genes, reproduction and inheritance in a microbe

该项目旨在特别探索疟原虫的性基因遗传，疟原虫是一大群人类和动物寄生虫的代表。疟原虫必须在蚊子体内有性交换基因，才能将疾病转移给新的宿主。该项目将研究疟原虫基因在繁殖过程中的命运和行为；由性遗传过程和一些疟原虫基因的不对称遗传引起的染色体状态的不同。该项目预计将提高澳大利亚了解这些寄生虫在蚊子载体中繁殖和生存的能力，并开发先进的遗传工具，这将推动全球微生物遗传学学科的发展。这可能最终导致生物技术和生物医学成果。

The project aims to particularly explore sexual gene inheritance in Plasmodium, a representative of a large group of human and animal parasites. Plasmodium must have a sexual exchange of genes in the mosquito for the transfer of disease to a new host. This project will investigate the fate and behaviour of Plasmodium genes during reproduction; the differing chromosome states resulting from sexual genetic processes and the asymmetrical inheritance of some Plasmodium genes. The project is expected to advance Australia’s ability to understand the reproduction and survival of these parasites in their mosquito vector and develop cutting-edge genetic tools that will advance the microbial genetics discipline globally. This may ultimately lead to biotechnology and biomedical outcomes.