EQUALIZATION TECHNIQUES IN MAMMOGRAPHY

经证实的乳房X光摄影在检测乳房疾病中的能力 微小的乳腺癌和相应的改善 预后已导致ACR/ACS建议对 国家乳房筛查方案。尽管有这样的潜力 受益于这些计划，它们的普遍实施还很遥远 从完整开始。主要障碍包括公众的担忧 关于辐射风险和攻击性不适 压缩、成本、后勤困难和剩余技术 在年轻患者群体中的局限性。它的目的是 本项目旨在研究提高乳房X光摄影图像质量的方法 通过组合应用改进的散射抑制来提高质量 和均衡化，以增强图像对比度 减少了辐射剂量。我们相信，这将改善 除原发灶外的所有患者的钼靶摄影的总体效果 对那些乳房致密、腺体浓密的人有好处 技术受到严重限制。我们将着手一项计划 为充分探讨均衡化在乳房X光检查中的作用 乳房均衡X线机样机的联合研制 系统(MSER)引导构建全面的临床 系统。我们将进行一些幻觉 用专门的拟人化乳房幻影进行实验 测量癌症和微钙化的检测 用ROC统计方法进行分析。这些研究将在 各种乳房体模配置，以模拟脂肪通过 到非常致密的腺体乳房。有限的临床评估将 跟着。

The proven capability of mammography in the detection of minimal breast cancers and the corresponding improvement in prognosis has led to the recommendation by the ACR/ACS for a national breast screening protocol. In spite of the potential benefit of these programs, their general implementation is far from complete. Primary obstacles include public concern regarding radiation risks and discomfort from aggressive compression, cost, logistical difficulties and remaining technical limitations in younger patient populations. It is the purpose of this project to study means of improving mammographic image quality by the combined application of improved scatter rejection and equalization to enhance image contrast with the potential for reduced radiation dose. We believe that this will improve the overall efficacy of mammography for all paients but with primary advantages for those with dense, glandular breasts where current techniques are severely limited. We will embark upon a program to fully explore the role of equalization to mammography by the combined development of a prototype equalization mammography system (MSER) leading to the construction of a fully clinical system. We will conduct a number of phantom perception experiments with specialized anthropomorphic breast phantoms measuring the detection of cancer and microcalcifications analyzed with ROC statistics. These studies will be done with various breast phantom configurations to simulate fatty through to very dense glandular breasts. A limited clinical evaluation will follow.