Anti-Campylobacter Biofilm Technologies, to improve safety and shelf life of poultry products (AC-BIT)

这一可行性项目将针对肉类供应链中微生物病原体形成的生物膜，以防止在人类食物链中传播。我们的模型将是弯曲杆菌和沙门氏菌的生物膜，这两种细菌是鸡皮/肉上存在的食物中毒的重要原因，塑料用于家禽包装材料。将特别注重使用食品级酶和可食用天然产品(如辣根活性物质)可能抑制和去除这类生物膜。这项研究将建立在病原体生物膜、家禽生产、包装生产和天然产品化学方面的多学科专业知识的基础上，这将为未来家禽包装或清洁产品行业抗生物膜产品的设计研究奠定基础，这些产品将用于随后的项目，用于地图托盘、浸泡垫或家禽产品的密封膜。这项工作将对英国的食物中毒产生影响，这是英国食品行业面临的一大挑战。据估计，约100万个病例每年给英国经济造成的损失为15亿英磅，受弯曲菌污染的家禽是英国食物中毒的主要单一原因，经济负担估计为5.83亿英磅。

This feasibility project will target biofilms formed by microbial pathogens in the meat supply chain, to prevent transmission in the human food chain. Our model will be biofilms of Campylobacter and Salmonella, two bacteria which are importantcauses of food poisoning present on chicken skin/meat, with plastics used in poultry packaging materials. A particular focus will be given to the possible inhibition and removal of such biofilms using food-grade enzymes and edible natural products(such as horseradish actives). The research will build-up on multi-disciplinary expertise in pathogen biofilm, poultry production, packaging production and natural product chemistry This will underpin future research on the design of antibiofilm products for the poultry packaging or cleaning product industry, which will be used in subsequent project for usagein MAP trays, soaker pads or sealing foils with poultry products. This work will have an impact on food poisoning in the UK, which represents a major challenge to the UK food industry. The cost to the UK economy of the ~1 million cases isestimated at £1.5 bn per annum, and poultry contaminated with Campylobacter is a major single cause of food poisoning in the UK, with a financial burden estimated to be £583 million.