THE MECHANISM OF MESSENGER-RNA TRANSLATION

该项目将采用2种方法来表征最初的步骤 使信使-RNA参与信使-RNA的正确启动 翻译。首先，这个项目将确定哪些核苷酸和 卫星烟草坏死病毒的翻译起始点附近 RNA(STNV RNA)是结合特定起始因子所必需的 在开始翻译这个信使-RNA之前。第二，这个 项目将探索与采用的一个或多个步骤 起始因子-STNV RNA复合体通过核糖体结构参与 这个信使--RNA的翻译。

This project will employ 2 approaches to characterize the initial steps that involve messenger-RNA in the correct initiation of messenger-RNA translation. First, this project will determine which nucleotides at and around the translation initiation site of satellite tobacco necrosis virus RNA (STNV RNA) are required for the binding of specific initiation factors prior to the initiation of translation of this messenger-RNA. Second, this project will explore the step or steps associated wih the uptake of initiation factor-STNV RNA complexes by ribosome structures involved in the translation of this messenger-RNA.