POLY ORGANOPHOSPHAZENES FOR BIOMEDICAL USES

我们打算继续努力开发聚磷腈聚合物，如 用作人造组织的半透性水凝胶和膜 用于药物缓释的膜、基质和基质 酶和其他生物活性物质的固定化。这项工作 将围绕着选择合适的亲水侧基 附着在聚合物链上的聚合物交联剂的发展 反应，并使用这些材料来调解小分子的扩散 分子溶质。生物兼容性研究也在计划中，将 通过合作研究安排进行。

We intend to continue our efforts to develop polyphosphazene polymers as hydrogels and membranes for use as artificial tissues, semipermeable membranes, matrices for the slow release of drugs, and substrates for the immobilization of enzymes and other biologically-active agents. The work will revolve around the selection of suitable hydrophilic side groups attached to the polymer chain, the development of polymer crosslinking reactions, and the use of these materials to mediate the diffusion of small molecule solutes. Biocompatibility studies are also planned, to be undertaken through a collaborative research arrangement.