用于生物医学用途的聚有机磷腈-猫眼课题宝

用于生物医学用途的聚有机磷腈

批准号：

3334420

负责人：

HARRY R ALLCOCK

金额：

$18.05万

依托单位：

PENNSYLVANIA STATE UNIVERSITY, THE

依托单位国家：

美国

项目类别：

财政年份：

1982

资助国家：

美国

项目状态：

已结题

起止时间：

1982-07-01 至 1991-03-31

来源：

https://reporter.nih.gov/project-details/3334420

关键词：

affinity chromatography antioxidants biomaterials chemical synthesis drug design /synthesis /production gel electrophoresis immobilized enzymes macromolecule polymers prosthesis solvolysis

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中文摘要

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英文摘要

We intend to continue our efforts to develop polyphosphazene polymers as hydrogels and membranes for use as artificial tissues, semipermeable membranes, matrices for the slow release of drugs, and substrates for the immobilization of enzymes and other biologically-active agents. The work will revolve around the selection of suitable hydrophilic side groups attached to the polymer chain, the development of polymer crosslinking reactions, and the use of these materials to mediate the diffusion of small molecule solutes. Biocompatibility studies are also planned, to be undertaken through a collaborative research arrangement.

期刊论文(3)

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科研奖励(0)

会议论文

Synthesis of a heparinized poly(organophosphazene).

DOI： 10.1016/0142-9612(82)90037-0

发表时间： 1982-04

期刊：

Biomaterials

影响因子： 14

作者：

[T. Neenan;H. Allcock]