PERINATAL DETERMINANTS OF DEVELOPMENT

这个项目试图刻画出持久和暂时的 儿童生理和行为发育的差异 一年中不同季节出生的动物，重点是 关于幼年动物如何决定一年中的季节和标准杆- 母亲在传达季节信息方面的特殊作用。 具体项目包括：1)确定预审和预审的作用 出生后光周期对生理和行为发育的影响； 2)确定母体褪黑激素在HER发育中的作用 后代；3)评估其他非褪黑素因子的作用 在母亲体内受到光周期的影响，进而影响幼崽 发育；4)确定幼崽是否在光周期中出生 一年中典型的不同季节对 出生后标准光周期；5)功能评估 幼崽发育差异在幼崽发育中的意义 母亲们模拟一年中不同季节的饲养员；6) 确定早期毛皮生长的重要性和持久性 在冬季光周期中，母亲所生的幼崽。建议数 工作可能导致概念和干预措施，可以提供 洞察出生季节如何改变肺炎的发病率 精神分裂症、酒精中毒与人类生长发育模式 人口。

This project seeks to characterize the enduring and temporary physiological and behavioral developmental differences among animals born during different seasons of the year, with emphasis on how young animals determine the season of the year and the par- ticular role of the mother in communicating seasonal information. Specific projects include: 1) determining the role of Pre- and postnatal photoperiod on physiological and behavioral development; 2) determining the role of maternal melatonin on development of her offspring; 3) assessing the role of other, non-melatonin factors affected by photoperiod in the mother that in turn influence pup development; 4) determining whether pups born in photoperiods typical of various seasons of the year respond differently to a standard photoperiod postnatally; 5) assessing the functional significance of differences in pup development in litters born to mothers simulating breeders from various seasons of the year; 6) determining the significance and permanence of early fur growth in pups born to mothers housed in winter photoperiods. The proposed work may lead to concepts and interventions that could provide insight into how season of birth alters the incidence of schizophrenia, alcoholism and growth pattern in the human population.