MODELING CAUSE-SPECIFIC MORTALITY IN INFANTS & TODDLERS

该项目的目标是提供一个统计模型， 婴儿和幼儿死亡率纵向研究分析， 为了更好地估计特定卫生干预措施对儿童的影响， 存在多种死亡原因和异质性（以 社会经济地位、可测量的生物脆弱性和未观察到的 异质性）。 这项工作将把死亡率分解为发病率 和病死率，因为对特定疾病的干预措施往往针对 或者是另一个 这些方法将扩大随机的统计工作， 影响和广义估计方程模型的情况下， 多项结果。 一个重要的成果将是量化手段， 疾病依赖 这项工作将主要依靠口头验尸 这是最近制定的一份调查问卷。 理论工作将 适用于婴幼儿发病率纵向数据集， 菲律宾宿务的死亡率。

The objective of the project is to provide a statistical model for the analysis of longitudinal studies of infant and toddler mortality in order to better estimate the effects of specific health interventions in the presence of multiple dependent causes of death and heterogeneity (in terms of socio-economic status, measured biological frailty and unobserved heterogeneity). The work will decompose mortality into disease incidence and case fatality since interventions for specific diseases often target on or the other of these. The methods will expand statistical work on random effects and generalized estimating equation models to the case of multinomial outcomes. An important outcome will be means to quantify disease dependence. The work will draw heavily on the verbal autopsy questionnaire that has been recently developed. The theoretical work will be applied to a longitudinal data set on infant and toddler morbidity and mortality in Cebu, The Philippines.