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TREATMENT OF MILD HYPERTENSION STUDY (TOMHS)

TREATMENT OF MILD HYPERTENSION STUDY (TOMHS)
轻度高血压的治疗研究 (TOMHS)
批准号：
3348072
负责人：
Richard Hugo Grimm
金额：
$96.16万
依托单位：
UNIVERSITY OF MINNESOTA
依托单位国家：
美国
项目类别：
财政年份：
1990
资助国家：
美国
项目状态：
已结题
起止时间：
1990-09-30 至 1993-09-29
来源：
https://reporter.nih.gov/project-details/3348072
关键词：
ACE inhibitors alcoholic beverage consumption alpha antiadrenergic agent antihypertensive agents behavior modification beta antiadrenergic agent blood chemistry blood pressure calcium channel blockers cardiovascular disorder chemotherapy cardiovascular disorder prevention clinical trials diuretics drug adverse effect echocardiography electrocardiography enalapril exercise heart dimension /size human middle age (35-64) human subject hypertension low salt diet myocardial ischemia /hypoxia nutrition related tag questionnaires statistics /biometry therapy compliance urinalysis weight control

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相关文献

中文摘要
翻译
本建议为“轻度”治疗的第一阶段续期而提出。
英文摘要
This proposal is for the renewal for Phase I of the Treatment of "Mild" Hypertension Study (T0MHS). The study will allow for long-term detailed assessment of 902 hypertensives prescribed one of five active drugs (representing major classes of medications currently in use) or placebo, using a randomized double-blind design. Each treatment group also is advised nonpharmacologic methods to control their blood pressure including weight loss, dietary sodium reduction, alcohol reduction and increased leisure-time physical activity. This proposal is for a 2 year and 7 month continuation which includes 2 additional years of follow-up and a final 7 months for close-out activities, data analysis and publications.
期刊论文(11)
专著(0)
科研奖励(0)
会议论文
Chlorthalidone attenuates the reduction in total cholesterol and small, dense LDL cholesterol subclass associated with weight loss.
氯噻酮可减弱与减肥相关的总胆固醇和小而密的低密度脂蛋白胆固醇亚类的减少。
DOI： 10.1093/ajh/6.7.636
发表时间： 1993
期刊： American journal of hypertension
影响因子： 3.2
作者： [Bradley,K, Flack,JM, Belcher,J, Elmer,P, Miller,P, GrimmJr,R]
通讯作者： GrimmJr,R
Efficacy and tolerance of antihypertensive treatment in men and women with stage 1 diastolic hypertension. Results of the Treatment of Mild Hypertension Study.
患有 1 期舒张期高血压的男性和女性抗高血压治疗的疗效和耐受性。
DOI： --
发表时间： 1996
期刊： Archives of internal medicine.
影响因子： --
作者： [Lewis,CE, Grandits,A, Flack,J, McDonald,R, Elmer,PJ]
通讯作者： Elmer,PJ
The treatment of mild hypertension study. A randomized, placebo-controlled trial of a nutritional-hygienic regimen along with various drug monotherapies. The Treatment of Mild Hypertension Research Group.
轻度高血压的治疗研究。
DOI： 10.1001/archinte.151.7.1413
发表时间： 1991
期刊： Archives of internal medicine
影响因子： --
作者： []
通讯作者：
The effects of sodium reduction on control of blood pressure elevation: a review.
减少钠摄入量对控制血压升高的影响：综述。
DOI： --
发表时间： 1987
期刊： Bibliotheca cardiologica
影响因子： --
作者： [Grimm,RH, Prineas,RJ]
通讯作者： Prineas,RJ
ASPirin in Reducing Events in the Elderly
ASPirin in Reducing Events in the Elderly
ASPirin in Reducing Events in the Elderly
ASPirin in Reducing Events in the Elderly
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