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THE MINNESOTA TWIN FAMILY REGISTRY

THE MINNESOTA TWIN FAMILY REGISTRY
明尼苏达双胞胎家族登记处
批准号:
3376339
负责人:
DAVID T LYKKEN
金额:
$17.12万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1987
资助国家:
美国
项目状态:
已结题
起止时间:
1987-07-01 至 1990-06-30

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中文摘要
翻译
从1936年到1955年在明尼苏达州出生的所有双胞胎都将被 通过出生记录来识别。 至少百分之80的 幸存的完整的配对将被招募参加 明尼苏达州双胞胎家庭登记处 我们预计招募4200人 1,000对同性双胞胎和1,000对异性双胞胎, 参与的双胞胎的配偶,以及至少500个双胞胎家庭 由双胞胎和他们的配偶组成,至少有一个后代 每对双胞胎,在某些情况下,对同性兄弟姐妹的 双胞胎和/或双胞胎的父母。 双胞胎招募是由 分级激励,这样我们就可以比较,在人口统计学上, 兴趣和性格变量的相似性, 招募对与其中一个或两个双胞胎是 不愿意参与,即,双胞胎通常不被研究。 所有 受试者将完成一份传记问卷,包括 健康、教育、职业和接合性信息, 受试者还将完成一系列性格和兴趣 库存。 作为明尼苏达州双胞胎研究的一部分 此外,当局亦正从一百对 在婴儿期分开抚养的双胞胎, 50个双胞胎的兄弟姐妹 数据将被分为4个年龄匹配的子样本, 通过复制分析。 这些数据将提供一个独特的 通过模型拟合技术评估相对 加性遗传、非加性(包括上位性或 “涌现”)遗传变异,共享和非共享的环境 对基本性状个体差异的贡献 个性和兴趣。 这些数据还将允许一个独特的 评估强迫性交配,配偶同化, 父母对这些变量的影响。 是 双胞胎家庭登记处将作为一个 持续的研究资源。
英文摘要
All twins born in Minnesota from 1936 through 1955 will be identified through birth records. At least 80 percent of the surviving intact pairs will be recruited to participate in the Minnesota Twin-Family Registry. We expect to recruit 4,200 pairs of same-sex and 1,000 pairs of opposite-sex twins, 4,000 spouses of participating twins, and at least 500 twin families consisting of both twins and their spouses, at least one offspring of each twin and, in some cases, pairs of same-sex siblings of the twins and/or both parents of the twins. Twin recruiting is by graded incentive so that we can compare, on demographic, interest, and personality variables, the similarity of easily recruited pairs with that of pairs in which one or both twins are reluctant to participate, i.e., twin pairs not usually studied. All subjects will complete a Biographical Questionnaire including health, education, occupation, and zygosity information, most subjects will also complete a battery of personality and interest inventories. As part of the Minnesota Study of Twins Reared Apart, the same measures are being obtained from 100 pairs of twins separated in infancy and reared apart and from the adoptive siblings of 50 of these twins. The data will be grouped into 4 age-match sub-samples to be analyzed by replication. These data will provide a unique opportunity for assessing by model-fitting techniques the relative importance of additive genetic, nonadditive (including epistatic or "emergenic") genetic variance, shared and unshared environmental contributions to individual differences in basic traits of personality and interest. The data will also permit a unique assessment of assortative mating, spousal assimilation, and parental influences in respect to these same variables. It is intended that the Twin-Family Registry will be maintained as a continuing research resource.
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THE MINNESOTA TWIN FAMILY REGISTRY
  • 批准号:
    2244566
  • 项目类别:
  • 资助金额:
    $16.84万
  • 财政年份:
    1991
  • 负责人:
    DAVID T LYKKEN
  • 依托单位:
TWIN/FAMILY STUDY OF VULNERABILITY TO SUBSTANCE ABUSE
  • 批准号:
    2117465
  • 项目类别:
  • 资助金额:
    $72.34万
  • 财政年份:
    1987
  • 负责人:
    DAVID T LYKKEN
  • 依托单位:
THE MINNESOTA TWIN FAMILY REGISTRY
  • 批准号:
    3376340
  • 项目类别:
  • 资助金额:
    $18.56万
  • 财政年份:
    1987
  • 负责人:
    DAVID T LYKKEN
  • 依托单位:
TWIN/FAMILY STUDY OF VULNERABILITY TO SUBSTANCE ABUSE
  • 批准号:
    3211243
  • 项目类别:
  • 资助金额:
    $1.61万
  • 财政年份:
    1987
  • 负责人:
    DAVID T LYKKEN
  • 依托单位:
海外基金