ELECTROPHYSIOLOGY OF LIMBIC NEURONS

电子记录将从不同的神经元中进行， 海马结构的部分（阿蒙角，齿状回， 下托、前下托、后下托、旁下托、内侧下托和 外侧内嗅皮层和外嗅皮层）的自由活动大鼠 用基于电视-计算机的系统定量分析。 对任务 这些区域的神经元， 当老鼠在特定位置或当老鼠的头 指向特定的方向，或者位置和 方向，即，来传递一些必要的信息 导航 从已知的情况来看， 导航信息可以被部分地勾画出来。 通过记录 从更多的地区，这种流动和转换应该成为 更清晰。 一个新的任务将被引入，其中大鼠将在 两种不同的环境。 此任务旨在专门测试 在不同环境中控制头部定向发射。 几乎 对导航的神经机制一无所知。 的 痴呆症患者往往会丧失导航能力， 严重的赤字，因为人们迷路了。 导航很复杂， 语言认知，以及流动和流动的细胞分析问题， 这种认知过程中表征的转换似乎 可解的

Eletrical recordings will be made from single neurons from different parts of the hippocampal formation (Ammon's horn, dentate gyrus, subiculum, presubiculum, postsubiculum, parasubiculum, medial and lateral entorhinal cortex and perirhinal cortex) in freely moving rats quantitatively analyzed with a TV-computer based system. In the tasks whichl will be used, neurons from some of these regions are known to fire when the rat is at a specific location or when the rat's head is pointing a specific direction, or some combination of location and direction, i.e., to signal information necessary for some kinds of navigation. From what is known already, the flow and transformation of navigational information can be partially sketched out. By recording from more regions, this flow and transformation should become much clearer. A new task will be introduced in which rats will move between two different environments. This task is designed to especially test the control of head directional firing across environments. Almost nothing is known about the neuronal mechanisms of navigation. The ability to navigate is often lost in dementia, and is an especially serious deficit because the people get lost. Navigation is complex non verbal cognition, and the problem of cellular analysis of flow and transformation of representations in this cognitive process seems solvable.