OXIDATIVE DAMAGE AND REPAIR

第五届国际自由基学会双年度会议 研究(SFRR国际)将被命名为“氧化损伤和 修理“，将于1990年11月14日至20日在帕萨迪纳举行， 加利福尼亚。会议对社会成员和非成员开放， 在平等的基础上，并被设计来吸引基础科学家， 临床科学家、毒物学家和临床医生。当前估计数 (根据SFRR国际过去的两年期会议，并要求 信息)表明可能有800至1,000名与会者在 那次会议。 在这一领域以前的会议都集中在基础科学上 自由基生物学的各个方面。虽然我们将讨论这一主题，但我们 计划突出当前最感兴趣的两个较新领域：1) “氧化应激”基因和蛋白质参与心肌损伤的修复 氧化损伤，以及2)在各种疾病中使用抗氧化剂疗法 疾病状态、急性损伤和慢性损伤(如延长 暴露在烟雾中)。氧化损伤的DNA、蛋白质和 脂类是一个新的研究领域的前沿研究 氧化应激。参与这种修复的许多酶系统 似乎是可诱导的氧化应激蛋白，会议将 提供第一个直接比较氧化应激和热量的论坛 休克基因和蛋白质。脑缺血/再灌注的抗氧化剂治疗 伤害(心脏病发作、中风等)、癌症(包括光动力学 治疗)、类风湿关节炎、动脉粥样硬化、烧伤/创伤、炎症、 各种眼部疾病正在研发中，或者已经在研发中。 正在进行临床试验。《氧化损伤与修复》将上映 关于自由基医学的这些重要方面的每一个会议。 SFRR国际由四个组成学会组成：SFRR欧洲、 SFRR日本、SFRR澳大拉西亚和氧气学会(‘SFRR America’)。这个 SFRR国际两年一度的会议是主要的国际会议 在这个蓬勃发展的跨学科领域。之前的两年一度的会议 曾在伦敦(1982)、约克(1984)、杜塞尔多夫(1986)和京都举行 (1988)，注册人数逐渐增加(950名与会者在 京都)。‘Me field还支持两种成功的期刊：《自由基 《生物学与医学》和《自由基研究通讯》。我们希望 吸引大量非会员加入《氧化损伤与修复》， 特别是心脏病学家、肿瘤学家、风湿病学家和 眼科医生，除了生物化学家，药剂学家， 毒物学家和分子生物学家。 关于“氧化损伤和修复”的科学计划被辩论和 由当地组委会(12名成员)根据提案批准 国际咨询委员会成员(18名成员中的41名成员 国家)。以确保最大限度地参与和介绍 最新研究和临床发现，会议将只邀请一些 占发言总人数的40%。大约60%的演讲者将 由届会主席从提交的摘要中选出。剩下的 摘要将在海报会议期间展示。一本抽象的卷 《自由基生物学与医学》，以及一本论文集 出版了。

The 5th Biennial Meeting of the International Society for Free Radical Research (SFRR International) will be entitled '"Oxidative Damage & Repair", and will be held from November 14-20, 1990 in Pasadena, California. The meeting is open to society members and non-members alike, on an equal basis, and has been designed to attract basic scientists, clinical scientists, toxicologists, and clinicians. Current estimates (based on past Biennial Meetings of SFRR International, and requests for information) indicate a potential registration of 800 to 1,000 conferees at the meeting. Previous meetings in this field have concentrated on the basic science aspects of free radical biology. Although this subject will be covered, we plan to highlight two newer areas of great current interest: 1) The involvement of "oxidative stress' genes and proteins in the repair of oxidative damage, and 2) The use of antioxidant therapies in various disease states, acute injuries, and chronic injuries (such as prolonged exposure to smog). The repair of oxidatively damaged DNA, proteins, and lipids is a new area of inquiry on the cutting edge of research into oxidative stress. Many of the enzymatic systems involved in such repair appear to be inducible oxidative stress proteins, and the meeting will provide the first forum for direct comparisons of oxidative stress and heat shock genes and proteins. Antioxidant therapies for ischemia/reperfusion injuries (heart attacks, strokes, etc), cancer (including photodynamic therapy), rheumatoid arthritis, atherosclerosis, burn/trauma, inflammation, and various diseases of the eye are being devised, or are already undergoing clinical trials. 'Oxidative Damage & Repair' will feature sessions on each of these important aspects of free radical medicine. SFRR International is comprised of four constituent societies: SFRR Europe, SFRR Japan, SFRR Australasia, and The Oxygen Society ('SFRR America'). The Biennial Meeting of SFRR International is the major international meeting in this blossoming interdisciplinary field. Previous Biennial Meetings have been held in London (1982), York (1984), Dusseldorf (1986), and Kyoto (1988), with progressively increasing registrations (950 conferees in Kyoto). 'Me field also supports two successful journals: "Free Radical Biology & Medicine', and 'Free Radical Research Communications'. We hope to attract large numbers of non-members to 'Oxidative Damage & Repair", particularly cardiologists, oncologists, rheumatologists, and ophthalmologists, in addition to biochemists, pharmacologists, toxicologists, and molecular biologists. The scientific program for "Oxidative Damage & Repair" was debated and approved by the Local Organizing Committee (12 members), based on proposals made by members of the International Advisory Board (41 members from 18 countries). To ensure maximal participation and the presentation of the latest research and clinical findings, the meeting will only invite some 40% of the total number of speakers. Approximately 60% of the speakers will be selected, by session chairs, from the submitted abstracts. The remaining abstracts will be presented during poster sessions. An abstract volume of 'Free Radical Biology & Medicine', and a proceedings book will be published.