FRAGILE X SYNDROME AND X-LINKED MENTAL RETARDATION

自第一次国际研讨会以来， 年贝塞斯达的脆性X综合征和X连锁精神发育迟滞 1983年，与这些有关的信息稳步增长。 紊乱 为此，需要一个论坛， 科学家和临床研究者进行讨论和交流 的想法。 1989年拟议的讲习班将集中于分子 和家庭研究，因为快速发展的技术 产生了新的信息。 其他重要议题的进展， 特别是X连锁精神发育迟滞的疾病分类学，临床 脆性X染色体的表型和行为方面 综合征（fra（X）），细胞遗传学，产前诊断，流行病学 和遗传学，和联系，将被审查和假设， 讨论了未来的研究问题。 该提案要求资金支付注册费， 有前途的美国初级调查员，他们的演讲将 在竞争的基础上选择。 还要求提供资金， 杰出科学家前往全体会议发言的旅费 会议，以及研讨会的领导人谁将招致 他们的工作之前或立即的重大开支 在研讨会之后。 旅行奖励将用于全体会议 通常不会出席本次会议的会议发言人，以及 对于被要求领导部门或担任主要职务的人， 委员会，但其机构或赠款不能提供充分的 支持. 如果这个应用程序得到资助，它将作出重大贡献 第四届脆弱X染色体国际研讨会 综合症和X连锁精神发育迟缓。

Since the first meeting of the International Workshop on the Fragile X syndrome and X-linked Mental Retardation in Bethesda in 1983 there has been a steady growth of information related to these disorders. For this reason a forum is needed to bring together scientists and clinical investigators for discussion and exchange of ideas. The proposed workshop in 1989 will focus on molecular and family studies since the rapidly evolving technology has yielded new information. Advances on other important topics, notably the nosology of X-linked mental retardation, clinical aspects of the phenotypic and behavioral aspects of fragile X syndrome (fra(X)), cytogenetics, prenatal diagnosis, epidemiology and genetics, and linkage, will be reviewed and hypotheses and future research issues discussed. The proposal requests funds to pay the registration fees of promising junior American investigators whose presentations will be chosen on a competitive basis. Funds are also requested to pay for the travel of distinguished scientists to address plenary sessions, as well as the leaders of the workshop who will incur significant expenses for their work prior to or immediately following the workshop. The travel awards will be for plenary session speakers who normally would not attend this meeting, and for persons who have been asked to lead sections or serve on key committees, but whose institution or grants cannot provide full support. If this application is funded, it will make a major contribution to the success of the 4th International Workshop on the Fragile X syndrome and X-linked Mental Retardation.