NEUROLOGICAL/NEUROPSYCHOLOGICAL ASPECTS OF HIV INFECTION

感染人类免疫缺陷病毒（HIV-1）的结果 不仅在免疫功能障碍方面， 神经心理疾病 百分之十的病人 获得性免疫缺陷综合征（艾滋病）有一个神经 作为他们患病的第一个迹象，37%的艾滋病患者 在他们的一生中，有75%的人患有严重的神经功能障碍， 尸检时发现有神经病理异常 据报道，8%至67%的患者存在神经心理异常 艾滋病患者和10%至40%的HIV-1感染者 感染 神经系统疾病的产生不仅是由于 机会性过程，也是原发性HIV-1的结果 神经系统感染。 因此， 感染HIV-1的人也有患神经系统或 神经心理疾病，即使在没有免疫 功能障碍或全身性疾病。 自从2004年首次报告HIV-1相关神经系统疾病以来， 1983年，研究神经学和神经心理学 艾滋病和HIV-1感染的并发症提供了一些 新的见解的机制和临床表现， HIV-1感染神经系统 神经学的目标 和艾滋病毒感染的神经心理方面，一个卫星 第五届世界艾滋病大会的会议，是汇集 世界上艾滋病毒感染各方面的专家及其 神经和神经心理并发症。 这些专家 首先将提供一个概述课程， 艾滋病和艾滋病毒感染的并发症。 本课程将 随后举行的会议期间， 回顾这一领域最重要的最新研究成果。 最后，在公开的科学会议上，来自世界各地的研究人员 世界将能够分享他们的研究成果， 这一领域，并有一个论坛，讨论这项研究。 这次国际科学会议将增加 神经和神经心理学方面的认识， 艾滋病和艾滋病毒感染;这一提高认识应导致 改善艾滋病毒感染者的护理， 并协调未来对这一关键领域的研究。

Infection with the human immunodeficiency virus (HIV-1) results not only in immunologic dysfunction but also in neurological and neuropsychological illness. Ten percent of all patients with the acquired immunodeficiency syndrome (AIDS) have a neurological complaint as their first sign of illness, 37% of AIDS patients have significant neurological dysfunction during their lifetime and 75% have neuropathological abnormalities on autopsy. Neuropsychological abnormalities have been reported in 8% to 67% of patients with AIDS and in 10% to 40% of people with HIV-1 infection. Neurological illness arises not only as a result of opportunistic processes but also as a result of primary HIV-1 infection of the nervous system. Thus, the large number of people infected with HIV-1 are also at risk of developing neurological or neuropsychological illness, even in the absence of immunological dysfunction or systemic illness. Since the first reports of HIV-1-related neurological illness in 1983, research into the neurological and neuropsychological complications of AIDS and HIV-1 infection has provided a number of new insights into the mechanisms and clinical manifestations of HIV-1 infection of the nervous system. The goal of Neurological and Neuropsychological Aspects of HIV Infection, a satellite meeting of the Vth World Conference on AIDS, is to bring together the world's experts in various aspects of HIV infection and its neurological and neuropsychological complications. These experts will first provide an overview course on the neurological complications of AIDS and HIV Infection. This course will be followed by a meeting during which several plenary talks will review the most important recent results of research in this area. Finally, during open scientific sessions, researchers from around the world will be able to share the results of their research in this field and have a forum for the discussion of this research. This international scientific meeting should result in an increased awareness of the neurological and neuropsychological aspects of AIDS and HIV infection; this increased awareness should result in improved care of patients with HIV infection as well as directing and coordinating future research into this critical area.