IUPS CONGRESS SMOOTH MUSCLE SYMPOSIUM

这份申请是为一个平滑肌肉研讨会提供部分资金，以 作为XXXII国际生理学联合会的一部分举行 科学(IUPS)大会于1993年8月1日至6日在苏格兰格拉斯哥举行。这 国会与前几届不同，由25个主题组成， 其科学内容将以研讨会的形式进行，并与 海报会议。每一次研讨会的组织者由 基于国际声誉的IuPS项目委员会。为了顺畅 肌肉研讨会主办方为栗山先生(九州大学)。、日本)、 A.P.Somlyo(大学弗吉尼亚州)和D.J.哈特肖恩(大学来自亚利桑那州)。 我们的研讨会将持续两天半的时间，包括五个环节。 将所有研讨会聚集在一起的大会的新颖组织 同样的地理位置，采用“戈登会议式”的格式 为学生和年轻人提供了一个独特的机会 研究人员对分子和细胞生理学进行了广泛的研究。一个 部分发言者名单包括许多国际公认的领导人 在各个方面都对平滑肌进行了研究。每节课都将开始 ，然后是研究演示文稿，以包括新的 事态的发展。时间被分配给展示激动人心的(到目前为止 身份不明)研究。要覆盖的领域包括：膜通道 (K+和Ca~(2+))，离子泵，体内Ca~(2+)浓度调节， 第二信使系统及其与收缩系统的整合 器械，跨桥自行车和能量学方面，调节 肌球蛋白磷酸化和细丝的作用机制及作用 分子生物学的调控及其在平滑肌中的应用 研究。在研讨会期间，我们将尝试将 细胞过程的分子机制。据我们所知，这是 只有在1993年举行的平滑肌肉会议，时间安排是理想的 讨论最近的发展，并促进未来的研究。进一步 研究对于了解正常的肌肉功能和 也是为了提高人们对病理生理状态和各种 平滑肌肌病。预计出席人数将超过6,000人，因此 潜在的接触和与各种各样的科学家的互动 (基础科学家和临床医生)几乎是无限的。另一个 吸引人的特点是，每个研讨会都集成在一个或 更多主题。在我们的例子中，两个主题是相关的，主题9、条纹和 心肌和主题10，肌肉。因此，许多基本的方面 肌肉功能(跨桥动力学、E-C偶联、钙通道、 等)将被呈现，在选择的肌肉中积累，即 平滑的肌肉。

This application is for partial funding of a Smooth Muscle Symposium to be held as part of the XXXII International Union of Physiological Sciences (IUPS) Congress in Glasgow, Scotland, in 1993, Aug 1-6. This congress is unique from its predecessors and is organized into 25 themes, whose scientific content will be in the form of symposia and associated poster sessions. The organizers of each symposium are selected by the IUPS program committee based on international reputation. For the Smooth Muscle Symposium the organizers are H. Kuriyama (Kyushu Univ. , Japan), A. P. Somlyo (Univ. of Virginia) and D. J. Hartshorne (Univ. of Arizona). Our symposium will extend over 2-1/2 days and consist of five sessions. The novel organization of the Congress that assembles all Symposia in the same geographic location with "Gordon Conference-style" formats will provide a unique opportunity for exposure of students and young investigators to a broad range of molecular and cellular physiology. A partial list of speakers includes many internationally recognized leaders in various aspects of smooth muscle research. Each session will begin with a review, followed by research presentations to include new developments. Time is allocated for the presentation of exciting (as yet unidentified) research. Areas to be covered include: membrane channels (K+ and Ca2+), ion pumps, regulation of internal Ca2+ concentrations, second messenger systems and their integration with the contractile apparatus, aspects of cross-bridge cycling and energetics, regulatory mechanisms and the roles of myosin phosphorylation and thin filament regulation and the application of molecular biology to smooth muscle research. During the symposium we will attempt to integrate the molecular mechanisms of cellular processes. To our knowledge this is the only smooth muscle meeting to be held in 1993 and timing is ideal to discuss recent developments and catalyze future research. Further studies are essential for an understanding of normal muscle function and also for an increased awareness of pathophysiological states and various smooth muscle myopathies. Attendance is expected to be above 6,000, thus potential exposure and interactions with a wide variety of scientists (basic scientists and clinicians) is virtually unlimited. Another attractive feature is that each Symposium is integrated within one or more themes. In our case two Themes are related, Theme 9, Striated and Cardiac Muscle and Theme 10, Muscle. Thus many fundamental aspects of muscle function (cross-bridge kinetics, E-C coupling, Ca2+ channels, etc.) will be presented, cumulating in the muscle of choice, namely Smooth Muscle.