THIRD AND FOURTH INTERNATIONAL CHROMOSOME 11 WORKSHOPS

这项赠款申请申请资金用于支持第三方和 第四届关于11号染色体的国际研讨会，会议是 旨在将主要实验室聚集在一起进行大规模 关于人类染色体的全球测绘项目，以及那些致力于 人类特定疾病基因的遗传作图和分离 11号染色体--第三届人类11号染色体国际研讨会 将于1992年9月14日至16日在加利福尼亚州圣地亚哥举行。这个 第四届国际研讨会将于9月在英国伦敦举行 1993年。这些会议紧跟着第一次和第二次非常成功的会议 年，11号染色体国际研讨会在马里兰州贝塞斯达举行 1989年，1991年在法国巴黎。这次会议将有100人参加 来自美国、加拿大、欧洲和欧洲实验室的调查人员 日本将讨论基因组研究的最新进展、新战略和技术 测绘，并促进信息和资源的交流。这个 会议的具体目标是：1)允许调查人员 提供关于11，2号染色体物理和遗传图谱的最新数据) 允许合成共识地图，并在可能的情况下促进联合 收集测绘数据，3)讨论和促进生产和使用 11号染色体社区的公共资源，4)收集 映射公共数据库中的数据，以及5)最终的规划策略 完成这一测绘项目。具体计划和进展情况 联合筛选11号染色体特异克隆的YAC文库， 分发参考图书馆和收集拟列入的数据 将在GDB中讨论。基因组数据库的代表以及 物理和基因测绘工作组、信息学和自动化 工作组将被邀请，以强调该社区的互动 和其他人在一起。与以往的研讨会一样，本次研讨会的成果将 发表在基因组学或《美国人类遗传学杂志》上。 第三届国际研讨会的组织者将是彼得·利特尔 (伦敦帝国理工学院)和格伦·埃文斯(索尔克研究所)。主办方 第四届国际研讨会将在第三届会议上确定 国际研讨会，但无疑将包括第三届的组织者 国际研讨会。

This grant application requests funds for the support of the Third and Fourth International Workshops on Chromosome 11, meetings which are designed to bring together major laboratories carrying out large scale global mapping projects on this human chromosome, and those groups working on the genetic mapping and isolation of specific disease genes on human chromosome 11. The third International Workshop on Human Chromosome 11 will be held in San Diego California, September 14 through 16, 1992. The fourth International Workshop will be held in London, England, in September of 1993. These meetings follow the highly successful First and Second International Workshops on Chromosome 11 held in Bethesda, Maryland, in 1989, and in Paris, France, in 1991. The meeting will bring together 100 investigators from laboratories in the United States, Canada, Europe and Japan to discuss recent progress, new strategies and technology for genome mapping, and to facilitate exchange of information and resources. The specific goals of the meeting will be to: 1) allow investigators to present recent data on physical and genetic mapping of chromosome 11, 2) allow synthesis of consensus maps and, wherever possible, facilitate joint collection of mapping data, 3) discuss and promote the production and use of common resources for the chromosome 11 community, 4) collection of the mapping data in a common database, and 5) planning strategies for eventual completion of this mapping project. Specific plans and progress on the joint screening of YAC libraries for chromosome 11-specific clones, distribution of reference libraries and collection of data to be included in GDB will be discussed. Representatives of the Genome Database, and physical and genetic mapping working groups, informatics and automation working groups, will be invited to emphasize interaction of this community with others. As with previous workshops, the results of this workshop will be published in Genomics or in the American Journal of Human Genetics. Organizers of the Third International Workshop will be Peter Little (Imperial College, London) and Glen Evans (Salk Institute). Organizers of the Fourth International Workshop will be determined at the Third International Workshop but will undoubtedly include organizers of the Third International Workshop.